Acquisition of the ability to produce polysaccharides from sucrose, i.e. the gtf gene encoding glucosyltransferase (GTF), is the key evolutionary event enabling dental biofilm formation by streptococci. To clarify the ancestry of streptococcal GTFs, time of its occurrence, and order of specific events, we investigated the distribution of GTFs among bacteria by phylogenetic analysis of the glyco...

Background: In the present study two hundred milk samples were collected from cows and buffaloes with no history of clinical mastitis in ongoing lactation, Sirohi district Southern Rajasthan. Methods: The pooled sample (collected each quarter) examined for status subclinical by Modified California test Somatic cell count respectively. Positive further investigated isolation identification major...

Gram-positive streptococci are non-motile, chain-forming bacteria commonly found in the normal oral and bowel flora of warm-blooded animals. Over the past decade, a proteomic approach combining 2-DE and MS has been used to systematically map the cellular, surface-associated and secreted proteins of human pathogenic streptococcal species. The public availability of complete streptococcal genomic...

BACKGROUND Strains of viridans group streptococci that initiate colonization of the human tooth surface typically coaggregate with each other and with Actinomyces naeslundii, another member of the developing biofilm community. These interactions generally involve adhesin-mediated recognition of streptococcal receptor polysaccharides (RPS). The objective of our studies is to understand the role ...

AIM The aim of this study was to examine whether bacteria associated with root canals possess genes that might predispose to bacterial colonization of the endocardium. METHODOLOGY Oligonucleotides were designed from DNA sequences encoding the functional binding regions of streptococcal fibronectin-binding protein (FnBP) and staphylococcal fibrinogen-binding protein (FgBP). The specificity and...

The outbreak of the post-streptococcal neurological disorders related to the antibasal ganglia antibodies is broadening. In addition to the disorders such as chorea and obsessive-compulsive disorder which have been recognized previously, the movement and behavioral abnormalities are the other aspects of post-streptococcal neurological disorders.  Streptococcus is a positive-gram and coccus...

Abstract Background Streptococcal infections are associated with life-threatening pneumonia and sepsis. The rise in antibiotic resistance calls for novel approaches to treat bacterial diseases. Anti-virulence strategies promote a natural way of pathogen clearance by eliminating the advantage provided bacteria their virulence factors. In contrast antibiotics, anti-virulence agents less likely ex...

Analysis of human buccal epithelial cells frequently reveals an intracellular polymicrobial consortium of bacteria. Although several oral bacteria have been demonstrated to invade cultured epithelial cells, several others appear unable to internalize. We hypothesized that normally noninvasive bacteria may gain entry into epithelial cells via adhesion to invasive bacteria. Fusobacterium nucleatu...

Questions concerning the precise anatomical location, the numbers and bacteriologic characteristics of hemolytic streptococci in streptococcal infections and in the carrier state are in need of clarification. This paper is a report of a study of these questions. The time-honored diagnostic aid for streptococcal infections is the practice of swabbing the posterior pharyngeal wall, the tonsils or...