نتایج جستجو برای: stoned

تعداد نتایج: 131  

Journal: :British Dental Journal 2003

Journal: :Nature 1970

Journal: :The Biochemical journal 2005
Leonard E Kelly A Marie Phillips

The stoned locus of Drosophila produces a dicistronic transcript and encodes two proteins, stoned-A (STNA) and stoned-B (STNB). Both proteins are located at synaptic terminals. The STNB protein contains a domain that has homology with the mu-subunit of the AP (adaptor protein) complex, as well as a number of NPF (Asp-Pro-Phe) motifs known to bind EH (Eps15 homology) domains. Mutations at the st...

Journal: :British Dental Journal 2003

Journal: :Cell reports 2014
Jasmin Podufall Rui Tian Elena Knoche Dmytro Puchkov Alexander M Walter Stefanie Rosa Christine Quentin Anela Vukoja Nadja Jung Andre Lampe Carolin Wichmann Mathias Böhme Harald Depner Yong Q Zhang Jan Schmoranzer Stephan J Sigrist Volker Haucke

Neurotransmission involves the exo-endocytic cycling of synaptic vesicles (SVs) within nerve terminals. Exocytosis is facilitated by a cytomatrix assembled at the active zone (AZ). The precise spatial and functional relationship between exocytic fusion of SVs at AZ membranes and endocytic SV retrieval is unknown. Here, we identify the scaffold G protein coupled receptor kinase 2 interacting (GI...

2009
Timo Kuosmanen Mika Kortelainen

Literature of productive efficiency analysis is currently divided between two main paradigms: the parametric Stochastic Frontier Analysis (SFA) and the deterministic, nonparametric Data Envelopment Analysis (DEA). This paper develops a new encompassing framework that melds the SFA-style stochastic composite error term to the DEA-type nonparametric frontier that satisfies monotonicity and concav...

Journal: :Annals of Allergy, Asthma & Immunology 2018

2010
Timo Kuosmanen Mika Kortelainen

The field of productive efficiency analysis is currently divided between two main paradigms: the deterministic, nonparametric Data Envelopment Analysis (DEA) and the parametric Stochastic Frontier Analysis (SFA). This paper examines an encompassing semiparametric frontier model that combines the DEA-type nonparametric frontier, which satisfies monotonicity and concavity, with the SFA-style stoc...

2010
Timo Kuosmanen

Electricity distribution network is a prime example of a natural local monopoly. In many countries, electricity distribution firms are regulated by the government. In Finland, the regulator estimates the efficient cost frontier using the data envelopment analysis (DEA) and stochastic frontier analysis (SFA) methods. This paper reports the main results of the research project commissioned by the...

2015
Chandni Hindocha Tom P. Freeman Grainne Schafer Chelsea Gardener Ravi K. Das Celia J.A. Morgan H. Valerie Curran

Acute administration of the primary psychoactive constituent of cannabis, Δ-9-tetrahydrocannabinol (THC), impairs human facial affect recognition, implicating the endocannabinoid system in emotional processing. Another main constituent of cannabis, cannabidiol (CBD), has seemingly opposite functional effects on the brain. This study aimed to determine the effects of THC and CBD, both alone and ...

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