In a previous paper (1) we discussed the relation of degree of gastric acidity of people without organic disease of the stomach to physical fitness, age, and other factors. It was shown that acidity tends to decrease with advancing years and that people in poor general physical condition, on the whole, have a less acid stomach juice than those who are fit. The present report deals with a simila...

To assess the influence of digestive juice on the pancreatic stump when pancreaticogastrostomy was performed after pancreatoduodenectomy, the pancreatic stump was anastomosed to the intact stomach (group I), the stomach after partial gastrectomy (group II), or the jejunum (group III) in rabbits, and the nature of the digestive juice at the anastomotic site as well as the histologic changes of t...

BACKGROUND Although current preoperative fasting guidelines apply restrictions to drinks containing milk because of delayed gastric emptying, the safe volume of milk that can be consumed up to 2 h before surgery on a theoretical basis has not yet been defined. We aimed to determine whether delayed gastric emptying depended mainly on the total amount of calories irrespective of compositional dif...

OBJECTIVE To measure pH, volatile fatty acid (VFA) concentrations, and lactate concentrations in stomach contents and determine number and severity of gastric lesions in horses fed bromegrass hay and alfalfa hay-grain diets. ANIMALS Six 7-year-old horses. PROCEDURE A gastric cannula was inserted in each horse. Horses were fed each diet, using a randomized crossover design. Stomach contents ...

The pharmacokinetics of fentanyl are complicated by an additional increase in plasma concentration during the elimination phase of the drug. We have confirmed that fentanyl is excreted in the gastric juice and reabsorbed from the alkaline medium of the small intestine. In addition, the stomach wall in rats has an important storage capacity for fentanyl. A maximum of about 20% of the dose was fo...

1. Concentrations of ascorbic acid (ascorbic and dehydro-ascorbic; A + D; measured by the 2,4-dinitrophenylhydrazine method) of nearly three times those of plasma are present in gastric juice samples from patients with normal gastric histology. 2. A significant reduction in gastric juice ascorbic acid (A + D) was observed in patients with chronic gastritis. This reduction in concentration was i...

The aim of this study was to determine the transport and distribution characteristics of levofloxacin in the rat stomach and investigate the effects of combination treatment with rabeprazole. A total of 160 Wistar rats were randomly divided into four treatment groups: 50 mg/kg levofloxacin, 100 mg/kg levofloxacin, 50 mg/kg levofloxacin + rabeprazole and 100 mg/kg levofloxacin + rabeprazole. For...

Samples of gastric juice were collected from 60 fasting subjects ranging from 10 to 80 years of age. Seventy-six per cent of the gastric cultures were positive. Natural gastric flora were classified into those organisms found frequently and sporadically. Effect of gastric pH on bacterial growth has indicated an increase in the number of samples showing growth above pH 5. Yeast was the only orga...

A WRITER, recently reviewing the known facts of the etiology of peptic ulcer, comments on the well-known observation that it is found in that part of the gastrointestinal tract that is directly exposed to gastric juice, and is subjected to the greatest mechanical stress by the passage of the gastric contents.1 Another established fact is the frequent association of ulcer with hyperchlorhydria, ...

2. Swine pyloric juice also exhibited two proteolytic pH maxima, at pH values 1-6 and 2-6, which are lower than those of swine or human fundic extracts or of human gastric juice. 3. Crystalline swine pepsin can be separated into two components, one of which digested proteins with pH maxima close to those found with swine fundic mucosa and the other with maxima close to those found with pyloric ...