Disc fragments are well known to migrate to superior, inferior, or lateral sites in the anterior epidural space, posterior epidural migrated lumbar disc fragments is an extremely rare disorder. Posterior epidural migrated lumbar disc fragments are often confused with other posterior epidural space-occupying lesions (cysts, abscesses, tumors, and hematomas). We reported the case of a 52- year-ol...

Background: Injury to the common peroneal nerve disrupts the motor control pathway to ankle dorsiflexors and evertors, as well as toe extensors, resulting in pathological gait and foot drop. Direct external compression on the fibular head is the most frequent cause of peroneal nerve impairment and has poor prognosis. Methods and Patients: Here, we report the surgical outcome of 21 patients with...

This article presents a noninvasive method of classifying gait patterns associated with various movement disorders and/or neurological conditions, utilizing unobtrusive, instrumented socks and deep-learning network. Seamless were fabricated using three accelerometer-embedded yarns, positioned at the toe (hallux), above heel, on lateral malleolus. Human trials conducted 12 able-bodied participan...

Background. Hereditary inclusion body myopathy is caused by biallelic defects in the GNE gene located on chromosome 9p13. It generally affects adults older than 20 years of age. Methods and Results. In this study, we present two Turkish sisters with progressive myopathy and describe a novel mutation in the GNE gene. Both sisters had slightly higher levels of creatine kinase (CK) and muscle weak...

BACKGROUND X-linked Charcot-Marie-Tooth disease type 5 (CMTX5) is caused by mutations in the gene encoding phosphoribosyl pyrophosphate synthetase I (PRPS1). There has been only one case report of CMTX5 patients. The aim of this study was to identify the causative gene in a family with CMTX with peripheral neuropathy and deafness. CASE REPORT A Korean family with X-linked recessive CMT was en...

BACKGROUND Posterior epidural migration of an extruded disk fragment is rare, and posterior migration of the free fragments causing cauda equina syndrome is exceptionally rare. The disk fragment must transgress through numerous anatomical restraints including the nerve roots in such cases. METHODS Two cases of migration of the sequestrated disk into the posterior epidural space are presented....

CLINICAL CASE, PART 1 A 19-month-old girl presented for neurologic consultation for delayed walking. She rolled at 6 months, sat unsupported at 8 months, but never walked independently. She babbled only. Her examination was notable for slightly decreased bulk in her legs, mild truncal hypotonia, and decreased deep tendon reflexes. She had difficulty pulling to stand and could only walk with sup...

cal – chest XP and CT revealed no lesion affecting the recurrent and/or vagus nerves. The family’s consent to perform tracheotomy was not obtained. At the age of 89, he was admitted to our hospital with pyrexia. On admission, neurological examination revealed new findings including right-sided dominant rigidity and Myerson’s sign. Resting tremor was absent. He showed severe dementia (MMSE 0/30)...

Pseudohypoparathyroidism type Ib (PHP-Ib) is a rare genetic disorder characterized by hypocalcemia and hyperphosphatemia due to imprinting defects in the maternally derived GNAS allele. Patients with PHP-Ib are usually identified by tetany, convulsions, and/or muscle cramps, whereas a substantial fraction of patients remain asymptomatic and are identified by familial studies. Although previous ...

A 39-year-old woman (gravida 1, para 1) was referred for episodic pain in her back and left leg associated with difficulties in walking. Clinical history revealed cyclic left sciatica that had evolved for longer than 3 years. Pain began on the first day of menstruation and continued for the 5 or 6 days of menstruation and recurred during the following cycle after a pain-free period. On examinat...