The development of an easily synthesized, modular, and tunable organic photoswitch that responds to visible light has been a long-standing pursuit. Herein we provide a detailed account of the design and synthesis of a new class of photochromes based on furfural, termed donor-acceptor Stenhouse adducts (DASAs). A wide variety of these derivatives are easily prepared from commercially available s...

The construction of a donor–acceptor Stenhouse adduct molecular layer on gold surface is presented. To avoid the incompatibility thiol surface-binding group with polyene structure switch, an interfacial reaction approach was followed. Poly(dopamine)-supported nanoparticles quartz slides were chosen as substrates, which expected to facilitate both and switching process by providing favorable ste...

Donor-Acceptor Stenhouse Adducts (DASAs) are molecular photoswitches that reversibly isomerize from a linear to cyclized form upon visible light irradiation. In the form, these molecules selectively react with thiol in thiol-Michael addition. Driven by complexity of switching mechanism and chemical properties DASAs, effect concentration (ranging 1 5 mM DASA) on addition was investigated. We fin...

•Thermal isomerization pathways of donor-acceptor Stenhouse adducts are tuned by polarity•Non-selective stimuli produce selective responses in the DASA mixture Natural systems such as cells or organisms consist thousands stimulus-responsive and adaptive molecules assemblies enzymes proteins. To achieve a multitude selectivity despite limited set available stimuli, nature relies on highly contro...

The wavelength-selective, reversible photocontrol over various molecular processes in parallel remains an unsolved challenge. Overlapping ultraviolet-visible spectra of frequently employed photoswitches have prevented the development of orthogonally responsive systems, analogous to those that rely on wavelength-selective cleavage of photo-removable protecting groups. Here we report the orthogon...

In the present investigation the action of sparteine sulphate alone and in combination with other drugs has been studied on isolated human uterine strips, from both pregnant and non-pregnant uteri. The effect of sparteine sulphate alone has been found to be dose dependant. Out of various combinations stilbesterol and priscol made a good combination for clinical use, however, further clinical st...

Center for Applied linguistiCs • 4646 40tH st nW • WAsHington dC 20016-1859 • 202-362-0700 • WWW.CAl.org Second language acquisition (SLA) researchers do not agree how instruction can best facilitate language learning. Given this lack of consensus, it might be thought unwise to attempt to formulate a set of general principles for instructed language acquisition. However, if SLA is to offer teac...