Within the heterogeneous architecture of tumour tissue there exists an elusive population of stem-like cells that are implicated in both recurrence and metastasis. Here, by using engineered extracellular matrices, we show that geometric features at the perimeter of tumour tissue will prime a population of cells with a stem-cell-like phenotype. These cells show characteristics of cancer stem cel...

We have compared the interface morphology at the stem-cement interface of standard Charnley stems with a satin finish (Ra = 0.75 microm) with identical stems which had been grit-blasted over their proximal third (Ra = 5.3 microm) to promote a proximal bond. The stems were cemented into cadaver femora using conventional contemporary cementing techniques. After transverse sectioning, we determine...

Environmental Flow Requirement (EFR) is defined as the flow that is necessary to ensure the existence of habitats in water resources systems. EFR is defined in rivers as flow index commonly. Tennant method is the most popular hydrological method in rivers and based on the historic flow data. The most common method of hydraulic rating method is the wetted perimeter method. Habitat simulation tec...

The article analyzes the experiential-based process of STEM. Accordingly, some learning situations and activities are introduced so that students could find minimum area for constant perimeter rectangles. Upon exploration activities, Scratch software, hypothetical garden in schoolyard, deemed to develop their competencies Mathematics, information, technology, critical thinking. At same time, al...

let e be the ellipse with major and minor radii a and b respectively, and pbe its perimeter, then p = lim 4 tan(p/n)(a + b + 2) σ a2 cos2 (2k-2)pi/n+ sin2 (2k-2)pi/n; where n = 2m. so without considering the limit, it gives a reasonable approxi-mation for p, it means that we can choose n large enough such that the amountof error be less than any given small number. on the other hand, the formul...