Stanozolol is a synthetic heterocyclic steroid with anabolic and androgenic properties, which has been abused by several high-profile professional athletes. Stanozolol is also used in veterinary medicine to increase appetite, cause weight gain and treat certain types of anemia. The detection of stanozolol metabolites in human urine for doping control purposes depends on the analytical method ap...

UNLABELLED BACKGROUND Anabolic androgenic steroids, such as stanozolol, are typically misused by athletes during preparation for competition. Out-of-competition testing presents a unique challenge in the current anti-doping detection system owing to logistic reasons. Analysing hair for the presence of a prohibited drug offers a feasible solution for covering the wider window in out-of-compet...

An analytical method for the determination of stanozolol and its metabolites, based on liquid chromatography mass spectrometry was validated and used during the preparation of lyophilised samples of bovine urine. A serie of lyophilised samples was prepared and characterised in terms of mass concentration of 16ß-hydroxy-stanozolol and homogeneity.

Objective: Stanozolol is an anabolic androgenic steroid (AAS) that widely used by teenagers and athletes in bodybuilding, sports, athletics. The potential effects of stanozolol kidney functions have not been defined. In this study we investigated the expression tumor suppressor protein phosphatase tensin homolog (Pten) mRNA levels phosphatidylinositol 4,5-bisphosphate 3 kinase (Pi3k) B (Akt1) s...

A 66-year-old male patient developed jaundice after 7 months of treatment with the anabolic steroid, stanozolol. When the drug was withdrawn he made a full and uneventful recovery. A liver biopsy showed the histology of a hypersensitivity reaction. This is believed to be the first time jaundice has been recorded with stanozolol therapy and the first time a hypersensitivity-type jaundice has bee...

Anabolic androgenic steroids are used in the sport context to enhance muscle mass and strength and to increase muscle fatigue resistance. Since muscle fatigue has been related to oxidative stress caused by an exercise-linked reactive oxygen species (ROS) production, we investigated the potential effects of a treatment with the anabolic androgenic steroid stanozolol against oxidative damage indu...

Stanozolol is a 17α-alkylated synthetic anabolic steroid used illegally by bodybuilders. We present a 19-year-old man who was taking 50 mg of stanozolol intramuscularly, every other day for 2 months, to improve muscle mass. On admission, his bilirubin concentration was 44.34 mg/dl. The serum levels of liver enzymes were normal, with only alanine aminotransferase being slightly elevated. Liver b...

1. Repeated doses of the anabolic-androgenic steroid stanozolol were assessed for their effects on agonistic behavior, motor activity, and body weight in both young and adult male laboratory mice. 2. Stanozolol significantly increased weight gain in young, but not older subjects, especially at the highest doses. 3. There were, however, no significant differences in motor activity or in ethologi...

Sixteen patients with idiopathic recurrent superficial thrombophlebitis were shown to have a defect of blood and tissue fibrinolytic activity. After six months' treatment with stanozolol their mean dilute blood clot lysis time and plasma fibrinogen fell significantly and the mean fibrin plate lysis area increased. Attacks of thrombophlebitis stopped completely in 13 patients, though five patien...

Fourteen patients with longstanding lipodermatosclerosis of their lower legs, secondary to venous disease in 11, were treated for three months with stanozolol, a drug that enhances fibrinolytic activity. No other treatment was given and no change made in existing treatment. All the patients improved. Two were cured in three months, three were able to stop treatment in the next three to 11 month...