In Drosophila peripheral neurogenesis, Notch controls cell fates in sensory organ precursor (SOP) cells. SOPs undergo asymmetric cell division by segregating Numb, which inhibits Notch signaling, into the pIIb daughter cell after cytokinesis. In contrast, in the pIIa daughter cell, Notch is activated and requires Sanpodo, but its mechanism of action has not been elucidated. As Sanpodo is presen...

Polarity is a shared feature of most cells. In epithelia, apical-basal polarity often coexists, and sometimes intersects with planar cell polarity (PCP), which orients cells in the epithelial plane. From a limited set of core building blocks (e.g. the Par complexes for apical-basal polarity and the Frizzled/Dishevelled complex for PCP), a diverse array of polarized cells and tissues are generat...

Asymmetric cell division (ACD) is a simple and evolutionary conserved process whereby a mother divides to generate two daughter cells with distinct developmental potentials. This process can generate cell fate diversity during development. Fate asymmetry may result from the unequal segregation of molecules and/or organelles between the two daughter cells. Here, I will review how fate asymmetry ...

This study aims to analyze the standard operating procedure (SOP) for filing an exceptional ceiling sales division at PT. Semen Baturaja (Persero) Tbk. uses a qualitative research design with case approach. Data was collected through interviews, document analysis, and observation of SOP submission process study's findings are whether Standard Operational Procedure Submission Special Ceilings ha...

background: the extraction of teeth for orthodontic purpose has always been a controversial subject in the speciality. the aesthetics impact of the soft-tissue profile might play a key role in deciding on premolar extraction or non-extraction (ne) treatment, particularly in borderline patients. the purpose of this cephalometric study was to examine the soft-tissue treatment effects of class ii ...

Multi-view face detection in open environments is a challenging task, due to the wide variations in illumination, face appearances and occlusion. In this paper, a robust method for multi-view face detection in open environments, using a combination of Gabor features and neural networks, is presented. Firstly, the effect of changing the Gabor filter parameters (orientation, frequency, standard d...