Production of concatemeric DNA is an essential step during HSV infection, as the packaging machinery must recognize longer-than-unit-length concatemers; however, the mechanism by which they are formed is poorly understood. Although it has been proposed that the viral genome circularizes and rolling circle replication leads to the formation of concatemers, several lines of evidence suggest that ...

Introduction We believe that existing techniques only address parts of the problem of assessing the safety of the software components of safety-critical systems. It is our belief that the main shortcomings of these existing techniques lie in their poor integration with each other and with the rest of the development process. We have identified three main areas where improved integration is nece...

Rapid developments in the biomedical sciences have increased the demand for automatic clustering of biomedical publications. In contrast to current approaches to text clustering, which focus exclusively on the contents of abstracts, a novel method is proposed for clustering and analysis of complete biomedical article texts. To reduce dimensionality, Cosine Coefficient is used on a sub-space of ...

comparative assessment of genetic diversity of 122 durum wheat genotypes (triticum turgidum l. var. durum) was performed using 73 ssap polymorphic fragments, 123 aflp polymorphic loci and 104 ssr alleles. ssap and aflp data showed a clear demarcation between the cultivars and landraces and ssr data classified cultivars and landraces according to their origin. furthermore, the estimated genetic ...

INTRODUCTION Outdoor workers are at risk of developing skin cancer because they are exposed to high levels of harmful ultraviolet radiation. The Outdoor Workers Sun Protection Project investigated sun protection strategies for high risk outdoor workers in rural and regional Australia. METHODS Fourteen workplaces (recruitment rate 37%) across four industries in rural and regional Queensland, A...

1 Background and Overview (section written by Alfred Hero) Many engineering applications require extraction of a signal or parameter of interest from degraded measurements. To accomplish this it is often useful to deploy ne grained statistical models; diverse sensors which acquire extra spatial, temporal, or polarization information; or multi-dimensional signal representations, e.g. time-freque...

Current cost accounting (CCA) was an important issue in financial accounting in the 1980s. In the UK, an accounting standard (SSAP 16, 1980) required supplementary CCA disclosures by large companies, but widespread noncompliance led to its being made non-mandatory in 1986 and completely withdrawn in 1988. The forces behind this failure were partly a decline in the rate of inflation, which made ...

Hybridization and introgression represent important means for the transfer and/or de novo origination of traits and play an important role in facilitating speciation and plant breeding. Two sets of introgression lines in Brassica napus L. were previously established by its intertribal hybridizations with two wild species and long-term selection. In this study, the methods of amplified fragment ...