back ground: the aim of this study was to characterize the immunohistochemical expression of galectin 1, 3, and 9 in normal oral epithelium, oral squamous papilloma, and oral squamous cell carcinoma. materials and methods: immunohistochemical staining for galectins 1, 3, and 9 was evaluated in 8 samples of normal oral squamous epithelium, 15 samples of oral squamous papilloma, and 41 samples of...

skin cancer is one of the most important type of cancers in the world. in this way, molecular investigation in order to detect some novel mechanisms and polymorphisms involved in cancer development can be impressive and vital. in this way, the aim of this study was the histopathological investigation of skin cancer and its relationship with polymorphism of cdkn2a gene. this case-control study w...

a primary intraosseous carcinoma (pioc) is a squamous cell carcinoma arising within the  jawbone andshould be differentiated from a malignant ameloblastoma.  it  is not due to arising from an odontogenic cyst or tumor. the possibility of the lesion being  a metastasis fromanotherprimary site should be considered, and excluded by a careful history and examination. the diagnosis of a pioc is rare...

A retrospective study was undertaken on patients with multiprimaries associated with vulva carcinoma, analyzing in particular 33 patients with double epidermoid primaries of the vulva and cervix. It is noted that 20.8% of patients with vuivar carcinoma had a second primary; this occurred more frequently in intraepithelial (33.3%) than in invasive (16.0%) vulvar carcinoma. While the commonest se...

primary de novo intraosseous carcinoma is a rare neoplastic lesion which commonly occurs in the jaws. it is an epithelial odontogenic malignancy arising from odontogenic epithelial residues in the bone rather than from a preexisting epithelial lesion. in the present case report, the clinical, radiological and histological features of primary de novo intraosseous carcinoma are discussed and its ...

A woman presenting with vulval lesions is to be examined and evaluated further before giving her the definitive diagnosis proposing treatment. As differential may vary from benign like lichen sclerosus, intraepithelial neoplasia or malignant squamous cell carcinoma. We are a case report wherein 70 year presented features similar carcinoma but was diagnosed as pseudoepitheliomatous hyperplasia o...

ocular surface may be involved by different neoplastic lesions ranging from benign to highly malignant. recognition of risk factors, clinical presentations, pathology, and different therapeutic modalities is essential for selecting an appropriate approach. this article deals with the proper approach to ocular surface squamous neoplasia (ossn) including conjunctival/corneal intraepithelial neopl...

background & objectives:  cd10 is a cell surface enzyme with metalloendopeptidase activity, also known as common acute lymphoblastic leukaemia antigen, which mainly serves as a marker for acute lymphoblastic leukemia (all). to date and to the best of our knowledge, only few comparative immunohistochemical studies have assessed cd10 expression in cutaneous epithelial neoplasms. our goal was ...