skin cancer is one of the most important type of cancers in the world. in this way, molecular investigation in order to detect some novel mechanisms and polymorphisms involved in cancer development can be impressive and vital. in this way, the aim of this study was the histopathological investigation of skin cancer and its relationship with polymorphism of cdkn2a gene. this case-control study w...

background & objectives:  cd10 is a cell surface enzyme with metalloendopeptidase activity, also known as common acute lymphoblastic leukaemia antigen, which mainly serves as a marker for acute lymphoblastic leukemia (all). to date and to the best of our knowledge, only few comparative immunohistochemical studies have assessed cd10 expression in cutaneous epithelial neoplasms. our goal was ...

background and objectives: squamous cell carcinoma of the tongue (sccot) is the most common malignant neoplasm in oral cavity. at the time of the diagnosis of sccot regional metastases with a high mortality rate are common, which is due to the extensive lymphatic system drainage of the tongue. although the level of healthcare has significantly improved, the survival rate is still low with an un...

back ground: the aim of this study was to characterize the immunohistochemical expression of galectin 1, 3, and 9 in normal oral epithelium, oral squamous papilloma, and oral squamous cell carcinoma. materials and methods: immunohistochemical staining for galectins 1, 3, and 9 was evaluated in 8 samples of normal oral squamous epithelium, 15 samples of oral squamous papilloma, and 41 samples of...

statement of problem: many studies have indicated that genetic disturbances are common findings in patients with oral squamous cell carcinoma (oscc). identification of these changes can be helpful in diagnostic procedures of these tumors. purpose: the aim of this study was to appraise the chromosomal disorders in blood and tissue patients with oscc. methods and materials: in this descriptive st...

background: oral cancer is among the 10 most common cancers worldwide with an increasing global incidence. compromised antioxidant defense system plays a role in occurrence of cancer. this study evaluated the salivary antioxidant level of oral cancer patients compared to a control group. patients and methods: this case-control study was conducted on 22 oral squamous cell carcinoma patients pres...

primary de novo intraosseous carcinoma is a rare neoplastic lesion which commonly occurs in the jaws. it is an epithelial odontogenic malignancy arising from odontogenic epithelial residues in the bone rather than from a preexisting epithelial lesion. in the present case report, the clinical, radiological and histological features of primary de novo intraosseous carcinoma are discussed and its ...

conclusions according to the low prevalence of hcmv in oscc, it seems that this virus plays a minor role in this kind of cancer at least in southeast of iran. more comprehensive studies are needed to investigate the oncomodulatory effect of this virus on oscc. results the mean age of the patients (66.7% female and 33.3% male) was 58.6 years. only three cases (6.3%) of the grade i, oscc biopsies...

background:non-melanoma skin cancer (nmsc), the most prevalent types being squamous cell carcinoma (scc) and basal cell carcinoma (bcc), is the most common type of malignancy in human beings. these neoplasms are more frequent in the elderly and fair skinned people and mainly occur on sun-exposed sites of the body. ultraviolet b (uvb) has a well-known effect in induction and promotion of growth ...

abstract background and aim: oral cancer is one of the most common cancers of the head and neck. considering the high prevalence and mortality percentage of oral cancer and the significant advances in immunology and identification of different cytokines, the aim of the present study was to compare the concentration of il8 in saliva of patients with oral squamous cell carcinoma (oscc) and health...