Endothelial cells distinguished by their epithelioid morphology have been recognized for many years. Rosai first characterized them as “histiocytoid” in appearance in 1979 and soon thereafter they became known by the more popularized term "epithelioid". By the early and mid 1980's this nomenclature was incorporated into classification schemes of epithelioid vascular tumors that included reactiv...

Epithelioid hemangioendothelioma is a relatively uncommon lesion usually presenting in soft tissues. The occurrence in the mediastinum is exceptional rare. Histologically, this tumor is characterized by epithelioid cells with intracytoplasmic vacuoles in a hyalinized or mucinous stroma. Occasionally, spindle cells or osteoclast-like giant cells can be observed. Herein, we present a case of epit...

patients of all ages and have a reported prevalence rate of 0.001-0.03% in autopsy series and a rate of 0.15% in echocardiac series (1). The majority of primary cardiac tumors are benign. The most common primary cardiac neoplasm is a myxoma, which accounts for approximately half of all cases. Other benign primary tumors include the papillary fibroelastoma, rhabdomyoma, fibroma, hemangioma, para...

The epithelioid hemangioendothelioma (EH) is an uncommon angiocentric neoplasm of borderline or intermediate malignant potential, between the hemangioma and conventional angiosarcoma. It is characterized by the proliferation of endothelial cells with epithelioid or histiocitóide morphology with vacuolated cytoplasm and occasional eosinophilic spindle cells. Shows potential for local recurrence ...

Kaposiform hemangioendothelioma is an aggressive endothelial-derived spindle cell neoplasm that occurs nearly exclusively during childhood and teenage years. The lesion grows rapidly and is often associated with Kasabach-Merritt syndrome.In this study a 24 days old male neonate who presented with an ill-defined deeply situated violaceous mass on his left arm is described. He had also anemia and...

Kaposiform hemangioendothelioma is an aggressive endothelial-derived spindle cell neoplasm that occurs nearly exclusively during childhood and teenage years. The lesion grows rapidly and is often associated with Kasabach-Merritt syndrome. In this study a 24 days old male neonate who presented with an ill-defined deeply situated violaceous mass on his left arm is described. He had also anemia an...

spindle cell neoplasms are defined as neoplasms that consist of spindle-shaped cells in the histopathology. spindle cell neoplasms can affect the oral cavity. in the oral cavity, the origin of the spindle cell neoplasms may be traced to epithelial, mesenchymal and odontogenic components. this article aims to review the spindle cell neoplasms of the oral cavity with emphasis on histopathology.  ...

Kaposiform hemangioendothelioma is a rare human vascular neoplasm. In veterinary medicine this tumor type was only recognized in the dog. Here we describe an unusual case arising in the urinary bladder of a Holstein-Friesian adult cow. Histologically the tumor presented a nodular proliferation of spindle cells, forming angular slits, often containing extravasated erythrocytes. Peripherically, w...