Neuronal Network Maturation In article number 2100830, Natascha Schaefer and co-workers show an immunocytochemical z-stack of a two week old three dimensional primary spinal cord composit. Proteins marked are VGAT (cyan), GlyR (magenta), Nuclei (DAPI). The MEW-scaffold shows autofluorescence in the DAPI-channel.

Zygapophyseal (z) joints (or facet joints) are a potential source of pain in nearly 15-45% of patients suffering from chronic spinal pain. There are no clinical features or imaging techniques pathognomonic for z-joint pain. Blockade of the medial branch of the spinal nerve primary posterior ramus, using fluoroscopic guidance to ensure positioning of the needle tip and low volumes of local anest...

BACKGROUND During the last few decades, focus of rehabilitation outcome has been redirected to the lifetime monitoring of quality of life. The purpose of this study was to investigate the differences in quality of life perceptions between participants with spinal cord injury and participants of typical population. METHODS This cross-sectional controlled study of 100 adults aged 18-65 years wa...

Girifl: Transüretral rezeksiyon planlanan geriatrik hastalarda anestezi kalitesi, hemodinamik parametreler ve olas› komplikasyonlar aç›s›ndan, intratekal levobupivakain ile tek doz ve sürekli spinal anestezi uygulamalar› karfl›laflt›r›ld›. Gereç ve Yöntem: Transuretral rezeksiyon planlanan 60 geriatrik hasta tek doz spinal anestezi (n=30) ve sürekli spinal anestezi (n=30) olarak iki gruba ayr›l...

OBJECTIVES Non-radiographic axial SpA (nr-axSpA) comprises those patients who may have clinical and laboratory features of SpA but do not have definite radiographic sacroiliitis. Bone loss (osteopenia or osteoporosis) is well recognized in AS, however, bone status in nr-axSpA is unclear. The aims of this study were to investigate BMD in patients with nr-axSpA and compare them with age- and sex-...

AIM To explain the variability in the behavioral response after spinal nerve ligation by investigating the relation between the development of neuropathic pain and the expression of inflammatory indicators, in dorsal root ganglia (DRG) and the spinal nerve. METHODS Ninety-six male Sprague-Dawley rats were randomly assigned to the modified spinal nerve ligation, sham, and control group. Testin...

BACKGROUND Postdural puncture headache (PDPH) is one of the common complications of spinal anesthesia; it is observed in 1-40% of cases involving spinal anesthesia. It can cause considerable morbidity and 40% of cases may require invasive treatments such as epidural blood patch. With the exception of invasive treatments such as an epidural blood patch, current standard treatment modalities have...

The size of head compartments (head and brain volume, intracranial volume, gray and white matter volume, cerebrospinal fluid volume) and their ratios were determined on the basis of magnetic resonance images of the head acquired in a reference population of 502 healthy subjects. Age-matched subgroups were selected to reveal gender-related differences and changes with age. Normative data are pro...

Objective: Spinal muscular atrophy is a lower motor neuron disease, but other parts of the body could be affected. This study compared bone mineral density with metabolism and physical growth rates in patients diagnosed spinal type 2 3. Material Methods: Twenty-six were included (15 for 11 3). Weights heights measured, standard deviation scores determined, body-mass index was calculated. Motor ...

UNLABELLED Low BMDs, short stature, hypogonadism, subclinical hypothyroidism, and IFG are found in 3.3, 10, 33, 16.6, 6.6, and 26.6 % of 30 pediatric β thalassemia major patients, respectively. Age is related with low Z-scores. Short stature and hypogonadism patients were older. These patients' monitoring in late childhood and early teenage for these complications is recommended. BACKGROUND B...