نتایج جستجو برای: sphere culture
تعداد نتایج: 316954 فیلتر نتایج به سال:
Increasing evidence suggests that cancers contain a small subset of cancer-initiating cells, so-called cancer stem cells (CSCs) that are capable of regenerating a tumor after chemoradiation therapy. Sphere forming ability is known to be one of properties of CSCs, but the significance remains unclear. The present study focused on sphere formation of human hepatoma cells in three-dimensional cult...
To quantitatively study the effect of delay on selection dynamics in long-term sphere culture of cancer stem cells (CSCs), a selection dynamic model with time delay is proposed.Theoretical results show that the ubiquitous time delay in cell proliferationmay be one of the important factors to induce fluctuation, and numerical simulations indicate that the proposed selection dynamical model with ...
Cancer stem cells (CSCs) are proposed to be responsible for tumor recurrence, metastasis and the high mortality rate of cancer patients. Isolation and identification of CSCs is crucial for basic and preclinical studies. However, as there are currently no universal markers for the isolation and identification of CSCs in any type of cancer, the method for isolating CSCs from primary cancer tissue...
Identity in recent decades, especially in social and national dimension, as one of the most key components of humanities and social sciences, considered very deeply by experts and scientists. This article attempts to examine national identity in the sphere of culture globalization and worldwide consumption culture. Because this culture includes different dimension, the article has done by the p...
BACKGROUND In the differentiation of mouse embryonic stem (ES) cells into neurons using the 5-stage method, cells in stage 4 are in general used as neural progenitors (NPs) because of their ability to give rise to neurons. The choice of stage 4 raises several questions about neural progenitors such as the type of cell types that are specifically considered to be neural progenitors, the exact ti...
Identification of gastric tumor-initiating cells (TICs) is essential to explore new therapies for gastric cancer patients. There are reports that gastric TICs can be identified using the cell surface marker CD44 and that they form floating spheres in culture, but we could not obtain consistent results with our patient-derived tumor xenograft (PDTX) cells. We thus searched for another marker for...
How stemlike are sphere cultures from long-term cancer cell lines? Lessons from mouse glioma models.
Cancer stem cells may mediate therapy resistance and recurrence in various types of cancer, including glioblastoma. Cancer stemlike cells can be isolated from long-term cancer cell lines, including glioma lines. Using sphere formation as a model for cancer cell stemness in vitro, we derived sphere cultures from SMA-497, SMA-540, SMA-560, and GL-261 glioma cells. Gene expression and proteomics p...
in cultural semiotics as posed by tartu-moscow circle the concepts of cultural sphere, border, and the (non)cultural other and the dialogue between this cultural self and that other on the borders are very critical. the mechanism of intercultural translation and the processes of inclusion and exclusion govern this intercultural dialogue. such communication between cultures, in order to be reali...
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