نتایج جستجو برای: spermatogenic cells
تعداد نتایج: 1384428 فیلتر نتایج به سال:
Recent studies have reported that caspase 7 has an apoptotic and nonapoptotic function. However, the relationship between caspase 7 and spermatogenesis remains unknown. This study aimed to investigate the possible function of caspase 7 during normal and abnormal spermatogenesis. The cleaved form of caspase 7 was detected in testis tissues at different postpartum times (5-14 weeks) by qRT-PCR, W...
BACKGROUND Sertoli cells nurse germ cells during spermatogenesis, and alterations of Sertoli cell functions have been suggested in cases of spermatogenic failures. METHODS In this work, we measured stem cell factor (SCF) and clusterin mRNA levels, by quantitative RT-PCR, in RNA extracted from testicular biopsies of 49 azoospermic patients classified according to testicular histology as having...
Sub-fertility is one of the most common problems observed in crossbred males, but the etiology remains unknown in most of the cases. Although proteomic differences in the spermatozoa and seminal plasma between breeds have been investigated, the possible differences at the sperm precursor cells and supporting/nourishing cells have not been studied. The present study reports the differential prot...
Spermatogenic cells differentiate in vivo while in continuous contact with the Sertoli cell. During differentiation, the spermatogenic cells and Sertoli cells form a number of morphologically distinct stage-specific adhesions. We describe an in vitro assay system for studying the adhesion of spermatogenic cells to Sertoli cell monolayers. Mixed populations of spermatogenic cells or enriched fra...
The effects of vinblastine sulphate, alone and in combination with other antimitotic agents, were tested in vitro on testicular tissue from the anuran, Xenopus laevis. Treatment with vinblastine alone resulted in dissolution of spindle and intercellular bridge microtubules, but centrioles and sperm tail axonemes remained intact. In addition, no paracrystalloid inclusions typical of those report...
Abstract Introduction: Researchers usually search for medications of infertility. Hence, this study was done to determine the effects of L-Carnitine and exercise on histological changes of testicular tissue after Boldenone steroid use in male rats. Objective: Assessment of the effects of L-Carnitine with Endurance training after Boldenone use on testicular tissue changes in male rats. Materi...
Background: Infertility problem affects young couples. One of the known causes of spermatogenic disorder is chemotherapy in patients with cancer. Since dividing cells are mainly affected by anticancer drugs, the aim of the present study is to investigate the preventive effect of GnRH antagonist on spermatogenic cell apoptosis produced by anticancer drug. Materials and Methods: In the present st...
Regular exercise can counteract the adverse effects of aging on the musculoskeletal and cardiovascular systems. In males, the normal aging process is associated with reductions in testosterone production and impaired spermatogenesis, but the underlying mechanisms and their potential modification by exercise are unknown. Here, we report that lifelong regular exercise (running) protects the teste...
Background: Exposure to glucocorticoids such as dexamethasone (Dex) leads to numerous changes in various biological systems including the reproductive system. The present study investigates the efficacy of curcumin (Cur), an active component of turmeric, to attenuate Dex-induced spetmatogenic defects in the mouse testicles. Materials and Methods: A total of 32 male mice were divided into four g...
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