OBJECTIVE To investigate DNA fragmentation by using terminal deoxyribonucleotidyl transferase-mediated dUTP nick-end labeling in relation to World Health Organization parameters and computer-aided sperm analysis (CASA) in sperm to determine the possibility of obtaining a correlation among CASA parameters, sperm morphology, and DNA fragmentation. DESIGN Sperm analysis according to World Health...

Introduction: tegrity is the most important component for transferring genetic information Sperm DNA fragmentation is considered a component of male infertility. Its assessment comprises conventional semen analysis of which emphasis is placed on its evaluation in fertility clinics. In this study, we investigate the relationship between sperm parameters of motility, morphology, concentratio...

OBJECTIVE To evaluate levels of sperm nuclear DNA damage in infertile men with normal and abnormal standard semen parameters. DESIGN Prospective study. SETTING Male infertility clinic. PATIENT(S) Ninety-two men seeking infertility treatment and 16 fertile volunteers. INTERVENTION(S) Standard semen analysis was performed according to the World Health Organization guidelines. MAIN OUTCO...

background: chromomycin a3 (cma3) staining has been used to assess protamine deficiency. the aim of this study was to determine credibility of cma3 along with semen parameters for assessment of fertility potential. materials and methods: semen analysis and cma3 staining were carried out on 234 fertile and 178 subfertile individuals. semen analysis was assessed according to who criteria. protami...

objective: antioxidants are essential for sperm motility. calligonum extract possesses the important antioxidants catechin and quercetin. this study investigates the effects of calligonum extract on sperm parameters and the rate of apoptosis in testes of aging male mice. methods: we initially performed a dose response test with using three doses of calligonum (10 mg/kg, 30 mg/kg and 50 mg/kg). ...

introduction: prevalence of infertility in general population is around 15-10 percent. intra- uterine insemination (iui) is one method for treatment of infertility. success rate of this method is affected by different factors. past studies have shown that induction of ovulation and iui has increased significantly the chance of pregnancy in the infertile couple, especially male factor infertilit...

backgrand: cotinine (cot) is a major degradation product of nicotine (nic). the participation of leptin in female reproduction is well-established, but any role in male reproductive function is at the best tenuous. objective: the aim of this study was to evaluate the in-vitro effects of nicotine, cotinine and leptin on sperm parameters in normal semen of non-smokers fertile men. materials and m...

Background Sperm DNA fragmentation is known as an important cause of male infertility. The influence of sperm DNA damage on reproductive potential has been subject of many studies indicating various results and remaining the subject controversial. In this study, we investigated differences of the semen parameters and intracytoplasmic sperm injection (ICSI) outcome according to sperm DNA fragmen...

introduction: semen parameters and specially sperm morphology is used for the assessment of semen sample and for the prediction of the fertilization. however there is semen samples with normal sperm morphology but with hidden sperm chromatin anomalies. since sperm morphology and chromatin anomalies reduce the fertilization rat independently, the purpose of this study is to consider the relation...

different methods have been used to evaluate the beneficial effect of varicocelectomy; these include semen parameters and pregnancy rate. due to high biological variability of semen parameters, sperm functional tests have been considered as an efficient end point in assessment of fertility. therefore, the aim of this study was to evaluate the effect of varicocelectomy on semen parameters and sp...