Background: It is relevant to highlight that there is not a precise and perfect report on either 95 percentile value (upper limit of normal range) or on appropriate reference intervals for serum PSA in Iranian population. Objective: To determine age-specific reference ranges for serum prostate-specific antigen (PSA) concentration and PSA density (PSAD) and prostate volumes in a population of he...

A mAb, 1-23, which recognizes a novel cell surface Ag on immature murine thymocytes (designated as IMT-1 for immature thymocyte antigen-1) was prepared. IMT-1 was found to be expressed on 40 to 50% of CD4-8- double negative (DN), 5 to 10% of CD4-8+, and 5 to 20% of CD4+8+ double positive (DP) thymocytes in adult mice, but not expressed on CD4+8- thymocytes or peripheral T lymphocytes. It was no...

background: nowadays, highly specific aptamers generated by cell selex technology (systematic evolution of ligands by exponential enrichment) are being applied for early detection of cancer cells. prostate specific membrane antigen (psma), over expressed in prostate cancer, is a highly specific marker and therefore can be used for diagnosis of the prostate cancer cells. the aim of the present s...

OBJECTIVE Carotid artery intima-media thickness (IMT) is an intermediate phenotype for atherosclerosis. In a community population (n=5400), we determined whether a parental history of myocardial infarction (MI) or stroke is associated with increased IMT and whether associations differ at specific sites in the carotid arterial tree. METHODS AND RESULTS Using regression modeling, the proportion...

conclusions using tzpsad as an adjunct to psa may improve the specificity of psa in the diagnosis of pca and decrease the number of unnecessary prostatic biopsies in iranian men with serum psa level < 20 ng/ml. results among 1120 men who were eligible for enrolment, prostate cancer was detected in 265 patients. mean serum psa levels were 9.7 ± 4.3 ng/ml and 8.5 ± 3.7 ng/ml in patients with and ...

Background and Objectives: This review aims to explore the use of inspiratory muscle training (IMT) in patients with mechanical ventilation (MV). The topics were related to its effect on the duration of MV or weaning, respiratory symptoms or lung function, inspiratory muscle strength (IMS) or endurance, functional ability, and quality of life (QoL).  Methods: Articles published in the last 10 ...

background: we aimed to value the usefulness of free to total prostate-specific antigen and prostate-specific antigen (psa) density for prostate cancer in the patients with psa levels of 4.0 ng/ml or less. methods: a total of 343 subjects with psa levels of 4.0 ng/ml or less were biopsied. all patients were divided into four groups according to the psa levels: 0 to 1.0 ng/ml, 1.1 to 2.0 ng/ml, ...

Carotid intima-media thickness (IMT) has been one widely used index of early carotid atherosclerosis. We speculated that the influence of blood pressure variability (BPV) on early carotid atherosclerosis may be varied by the location of the carotid artery and diabetes history. Thus, the goal of this study was to evaluate the effects of BPV on early arteriosclerosis progression in different segm...

background: prostate cancer is the most common malignancy among the male population in the united states and the 3rd most common non-skin cancer among men in iran. its prevalence has shown a rising trend in recent decades. the aim of this study was to report the epidemiological features of prostate cancer in patients referred for prostate biopsy in the south of iran and to evaluate the accuracy...

background: prostate specific antigen (psa) is a protein currently used in vconjunction with the digital rectal examination to detect and guide management of prostate cancer. there are several causes of increase in serum psa including urological manipulations, medications, prostatic diseases, prostate cancer, prostate inflammation or infection, etc. some studies had reported cystoscopy to cause...