The likelihood ratio spatial scan statistic has been widely used in spatial disease surveillance and spatial cluster detection applications. In order to better understand cluster mechanisms, an equivalent model-based approach is proposed to the spatial scan statistic that unifies currently loosely coupled methods for including ecological covariates in the spatial scan test. In addition, the uti...

BACKGROUND Early detection of disease outbreaks enables public health officials to implement disease control and prevention measures at the earliest possible time. A time periodic geographical disease surveillance system based on a cylindrical space-time scan statistic has been used extensively for disease surveillance along with the SaTScan software. In the purely spatial setting, many differe...

BACKGROUND The spatial scan statistic proposed by Kulldorff has been applied to a wide variety of epidemiological studies for cluster detection. This scan statistic, however, uses a circular window to define the potential cluster areas and thus has difficulty in correctly detecting actual noncircular clusters. A recent proposal by Duczmal and Assunção for detecting noncircular clusters is shown...

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BACKGROUND Spatial scan statistics are widely used for spatial cluster detection, and several parametric models exist. For continuous data, a normal-based scan statistic can be used. However, the performance of the model has not been fully evaluated for non-normal data. METHODS We propose a nonparametric spatial scan statistic based on the Wilcoxon rank-sum test statistic and compared the per...