This is the story of how a conventional middle-class American household?a surgeon, his wife and three normal children?had first to recognise, then to cope with and, finally, to exclude, an abnormal family member. Tony was a beautiful child, the eldest, and apart from long hours of screaming for no apparent reason, he seemed a normal baby. His intellectual and motor development was average, but ...

The natural environment is in a state of constant flux and living organisms are perpetually challenged to adapt to these changes. Yet the mechanisms of adaptation, which lead to the development of new characteristics or behaviours, have troubled philosophers and scientists since the days of ancient Greece. In fact, it was not until 1859, when Charles Darwin (1809– 1882) published The Origin of ...

LYDIE BOULLE, M.D. GRMEK, CATHERINE LUPOVICI, and JANINE SAMIONCONTET, Laennec. Catalogue des manuscrits scientifiques, Paris, Masson, 1982, 4to, pp. vi, 316, Fr. 200.00. The scientific manuscripts of Laennec, among them such important unpublished items as his course in the College de France embracing all of medicine, or a book on pathological anatomy, are now distributed in five libraries in t...

Exposing male mice to nicotine or cocaine enables their male offspring to cope with high doses of either, which suggests that such paternal effects are generic, rather than being a response to a specific type of stress.

Exterior night, cityscape. Thousands of distant points of light lie still in the summer air. Below them a neon diner sign flickers silently across a nearby empty street. Suddenly the close up face of the main character moves into the frame, the focus pulls, bringing their silent profile into crisp silhouette, while blurring the urban backdrop into a splash of color. Each point of light blooms i...

Pelger-Huet anomaly is a rare autosomal dominant disorder characterized by pince-nez appearance of the nuclei of the neutrophils. This is caused by failure of nuclear segmentation due to genetic defect in the LBR (laminin B-receptor) on the chromosome 1q41-43. Heterozygotes have dumbbell-shaped or hyposegmented neutrophils with coarse chromatin and normal granules. Homozygotes have neutrophils ...

Woolson. (Frederick Midler, 18s.). This is the account of his adult son's psychotic illness by an American journals and of the way in which members of his family tried to readjust themselves to its effects upon their lives and personalities. The narrative is a painful one, and the author?deeply involved by his oW almost desperate efforts to help his son and to understand the changes in him^ wri...