abstract a solitary plasmacytoma of bone occurs in approximately 2-5% of patients with myeloma. the lesion mostly found in the axial skeleton and have infrequently been reported to arise in the hand, and usually occur in the distal phalanges. we report the interesting case of a 75-year-old man who developed a solitary lytic lesion of the thumb proximal phalanx. this lesion was explored through ...

Introduction: Plasmacytoma is monoclonal neoplastic proliferation of plasma cells. It can be either solitary or multiple and skeletal or extraskeletal. Solitary plasmacytoma is most frequently seen in vertebrae and secondarily in long bones. Its presence in jaws is extremely rare. Case Report: Here we report a case of plasmacytoma in the right side of mandible, a chronology for diagnosis of the...

Plasmacytoma is a plasma cell neoplasm that locally infiltrates a bone or spreads to extramedullary areas. A new World Health Organization criterion defines solitary plasmacytoma of bone as a localized bone tumor consisting of plasma cells identical to those seen in plasma cell myeloma, which is manifested as a solitary osteolytic lesion in a radiological evaluation. Primary tumors of the stern...

solitary plasmacytoma of bone is a rare malignant tumor mostly involving the axial skeleton. the tumor occurs in middle- aged or elderly people (mean age: 55 years) and has a high risk of progression to multiple myeloma. radiotherapy is the preferred treatment for this disease. we report a case of recurrent solitary plasmacytoma of the fourth lumbar vertebra in a 35-year-old male. the patient s...

OBJECTIVE To describe the imaging features of pelvic solitary plasmacytoma and to correlate them with the pathologic grade. MATERIALS AND METHODS A retrospective study was performed on the imaging features of 10 patients with a histological diagnosis of pelvic solitary plasmacytoma. The imaging studies were assessed for bone expansion, cortical destruction, signal intensity/density of soft ti...

Solitary plasmacytoma of the bone is a plasma cell tumor characterized by a single bone lesion with no evidence of myeloma elsewhere, including fewer than 5% plasma cells in the bone marrow. Although median age is about 14 years younger than that of patients with multiple myeloma, both diseases are extremely uncommon under 30 years of age. Solitary plasmacytoma of bone seem to have a prediction...

Extramedullary disease in plasma cell disorders can occur as a solitary plasmacytoma or can involve multiple sites with vastly different clinical outcomes. The article by Khaliq et al reports an unusual case of solitary extramedullary plasmacytoma (SEP) of the bladder in which the patient had a favorable outcome with lenalidomide/dexamethasone after failing first-line treatment with radiotherap...

Plasmacytoma is a localized collection of malignant plasma cells. The disease is divided into Solitary plasmacytoma of the bone (SPB) and extramedullary plasmacytoma (EMP) which are both distinct entity. SPB usually occur in the bones characteristically affected in multiple myeloma and EMP was most frequently located in the oronasopharynx and paranasal sinuses, with a 15-30% incidence of region...