Malignant melanoma Is an a^resslve, therapy-resistant malignancy of melanocytes. The incidence of meianoma has l>een steadily increasing worldwide, resulting In an increasing pubiic health problem. Exposure to solar UV radiation, fair skin, dysplastlc nevi syndrome, and a family history of meianoma are major risk factors for melanoma development. The interactions between genetic and environment...

The therapeutics of tumor is largely confined upon directly encountering the tumor cells. The current cytostatic agents mainly interfere with processes involved in cell growth while the aim in immunotherapy is to make immune effector cells to selectively attack the tumor cells. A recent approach to fight tumor is to impede and interfere with its blood supply, i.e., turning off angiogenesis or n...