CONTEXT Soft tissue tumors are composed of numerous and complex diagnostic entities. Because of this complexity and the recognition of an intermediate malignancy category including some tumors with a deceptively bland histologic appearance, soft tissue tumors may represent a major diagnostic challenge to the general practicing pathologist. OBJECTIVE To correctly diagnose soft tissue tumors wi...

the application of laser in dentistry is considered as a favorable technique for patients due to its many advantages compare to other current methods. one of the main goals in pediatric dentistry is to provide the treatment as comfortable as possible without any risks for the care. laser is being used in different pediatric dental conditions including caries detection, caries removal and cavity...

MDM2 and CDK4 immunostaining can be useful adjuncts in diagnosing liposarcoma among soft tissue neoplasms. We examined the reproducibility of MDM2 and CDK4 staining between 2 laboratories and between tissue microarrays and whole tissue sections. Sixty-two soft tissue tumors were immunostained at the Bergonié Institute, Bordeaux, France, and the Curie Institute, Paris, France. We also examined 2...

Plasma-cell neoplasms are classically categorized into four groups as: multiple myeloma (MM), plasma-cell leukemias, solitary plasmacytomas (SP) of the bone (SPB), and extramedullary plasmacytomas (EMP). These tumors may be described as localized or diffuse in presentation. Localized plasma-cell neoplasms are rare, and include SP of the skeletal system, accounting for 2-5% of all plasma-cell ne...

background:   although the majority of soft tissue masses are benign, it is important to consider malignancy in differential diagnoses. because most soft tissue sarcomas present as a painless mass, clinicians must watch for signs suggestive of malignancy, including large size, rapid growth, and site deep into the deep fascia.the purpose of this study was to determine the relative prevalence acc...

BACKGROUND Soft-tissue neoplasms embody a histologically diverse group of mesenchymal tumors. Oftentimes the histopathological diagnosis of soft-tissue tumors is challenging due to overlapping pathological features. METHODS We reviewed the current and most importantly known recurrent or tumor-specific genetic abnormalities involving soft-tissue tumors, focusing on how they are useful in worki...

The purpose of this article is to review soft tissue and bony enlargements that typically occur in the oral and perioral region of children. In order to organize these lesions into a thorough but comprehensible format, the principles of differential diagnosis must be used. All oral enlargements are broadly classified as soft tissue or bony abnormalities. Determination of the specific lesion cat...