In this paper, we propose several improvements on the block-coordinate Frank-Wolfe (BCFW) algorithm from Lacoste-Julien et al. (2013) recently used to optimize the structured support vector machine (SSVM) objective in the context of structured prediction, though it has wider applications. The key intuition behind our improvements is that the estimates of block gaps maintained by BCFW reveal the...

We address the identification of optimal biomarkers for the rapid diagnosis of neonatal sepsis. We employ both canonical correlation analysis (CCA) and sparse support vector machine (SSVM) classifiers to select the best subset of biomarkers from a large hematological data set collected from infants with suspected sepsis from Yale-New Haven Hospital's Neonatal Intensive Care Unit (NICU). CCA is ...

Survival analysis is a fundamental tool in medical research to identify predictors of adverse events and develop systems for clinical decision support. In order to leverage large amounts of patient data, efficient optimisation routines are paramount. We propose an efficient training algorithm for the kernel survival support vector machine (SSVM). We directly optimise the primal objective functi...

In this paper, we propose a novel method based on support vector machine (SVM) for microarray classification and gene (feature) selection. The proposed method, called similaritybased SVM (SSVM), incorporates the prior knowledge of gene similarity into the standard SVM by combining the standard l2 norm and the similarity penalty of all the genes. The preliminary experiments show that our method ...

BACKGROUND Chemical compounds and drugs (together called chemical entities) embedded in scientific articles are crucial for many information extraction tasks in the biomedical domain. However, only a very limited number of chemical entity recognition systems are publically available, probably due to the lack of large manually annotated corpora. To accelerate the development of chemical entity r...

This paper extends the previous work in smooth support vector machine (SSVM) from binary to k-class classification based on a single machine approach and call it multi-class smooth SVM (MSSVM). This study implements MSSVM for a ternary classification problem and labels it as TSSVM. For the case k > 3, this study proposes a one-vs.-one-vs.-rest (OOR) scheme that decomposes the problem into k(k −...

Building high accuracy speech recognition systems with limited language resources is a highly challenging task. Although the use of multi-language data for acoustic models yields improvements, performance is often unsatisfactory with highly limited acoustic training data. In these situations, it is possible to consider using multiple well trained acoustic models and combine the system outputs t...

In this paper, we explore the use of deep convolution and deep belief networks as potential functions in structured prediction models for the segmentation of breast masses from mammograms. In particular, the structured prediction models are estimated with loss minimization parameter learning algorithms, representing: a) conditional random field (CRF), and b) structured support vector machine (S...

We study the problem of learning an optimal subset from a larger ground set of items, where the optimality criterion is defined by an unknown preference function. We model the problem as a discriminative structural learning problem and solve it using a Structural Support Vector Machine (SSVM) that optimizes a “set accuracy” performance measure representing set similarities. Our approach departs...