Spliceosome-mediated RNA trans-splicing, or SMaRT, is a promising strategy to design innovative gene therapy solutions for currently intractable genetic diseases. SMaRT relies on the correction of mutations at the post-transcriptional level by modifying the mRNA sequence. To achieve this, an exogenous RNA is introduced into the target cell, usually by means of gene transfer, to induce a splice ...

OBJECTIVE The purpose of this study was to evaluate the surface roughness (SR) of 2 types of orthodontic archwires made by 4 different manufacturers. METHODS This in vitro experimental study was conducted on 35 specimens of 7 different orthodontic archwires, namely, 1 nickel-titanium (NiTi) archwire each from the manufacturers American Orthodontics, OrthoTechnology, All-Star Orthodontics, and...

Self-healing is an essential property of smart concrete structures. In contrast to other structural metals, shape memory alloys (SMAs) offer two unique effects: shape memory effects, and superelastic effects. Composites composed of SMA wires and conventional cements can overcome the mechanical weaknesses associated with tensile fractures in conventional concretes. Under specialized environments...

This paper presents a new approach for realizing a smart, fault tolerant, controllable and asset efficient power grid through the use of massively-dispersed mass-manufactured communicationsenabled sensor, power-converter and actuator networks. One example is ‘Smart Wires’, implemented using many modules of a Distributed Static Series Compensator (DSSC) device that can be clamped on to existing ...

Smart homes have emerged because people wanted to improve and optimize the comfort in their homes, minimizing at the same time daily home responsibilities. The first automated home systems have been presented at the Chicago and New York World Fairs in 1934 and 1939. Introducing more wires in the home was carried out by some hobbyists in the 1960-ies but at the time, technologies did not offer t...

Spinal disease is a common yet important condition that occurs because of inappropriate posture. Prevention could be achieved by continuous posture monitoring, but most measurement systems cannot be used in daily life due to factors such as burdensome wires and large sensing modules. To improve upon these weaknesses, we developed comfortable "smart wear" for posture measurement using conductive...

We report experimental laboratory studies on developing conductive pathways, or wires, using protoplasmic tubes of plasmodium of acellular slime mould Physarum polycephalum. Given two pins to be connected by a wire, we place a piece of slime mould on one pin and an attractant on another pin. Physarum propagates towards the attract and thus connects the pins with a protoplasmic tube. A protoplas...

In shape memory alloys the Thermoelastic Martensitic Transformation (TMT), intrinsically stepwise, can be either thermally induced or stress-induced. Moreover, it has already been shown that an extrinsic fragmentation of thermally induced transformation can be stimulated ("Step-wise Martensite to Austenite Reversible Transformation", SMART) by means of Incomplete Cycles on Heating (ICHs): the S...

Abstract Nickel Titanium Naval Ordinance Laboratory (NiTiNOL) is widely called as a shape memory alloy (SMA), class of nonlinear smart material inherited with the functionally programmed property varying electrical resistance during transformation enabling to be positioned sensing element. The major challenge instrument SMA wires suppress wires’ nonlinearity by proper selection two important fa...

Abstract The use of Shape Memory Alloy (SMA) recently increased in smart structures. It is essential to investigate the impact viscoelastic material, and transformation temperatures SMA on dynamic behavior, especially damping capability reinforced composite. In this paper, constants material are evaluated experimentally, a model based experimental results proposed for effect wires combination s...