In this paper, a new method is proposed to optimize a multi-response optimization problem based on the Taguchi method for the processes where controllable factors are the smaller-the-better (STB)-type variables and the analyzer desires to find an optimal solution with smaller amount of controllable factors. In such processes, the overall output quality of the product should be maximized while t...

The interesting debate between Parker and Anderson & Haddad (2003) suggests more fundamental reasons to question prevailing research paradigms and designs in respect of the efficacy of and indications for psychotropic medicines. That the clinical trial industry reveals even marginal drug effects may be seen as surprising given the virtual absence of any basis for a taxonomy of mental disorders,...

How do young children decide to trust testimony that contradicts their initial beliefs? The current study examined whether children rely on cues to informant credibility (i.e., history of accuracy) to determine if they would endorse an unexpected label from an informant. Threeand 4-year-olds (N = 60) saw a picture of a hybrid artifact that consisted of features of two typical familiar artifacts...

INTRODUCTION Cobicistat, a component of stribild (STB), is known to inhibit renal creatinine secretion. A detailed analysis of the renal safety profile of STB in two Phase 3b switch studies of virologically-suppressed individuals on stable therapy: STRATEGY(S)-PI (STB vs a RTV-boosted protease inhibitor [PI] with emtricitabine and tenofovir DF [FTC/TDF]); and STRATEGY(S)-NNRTI (STB versus a non...