In a double-blind cross-over study, the effects of slow release (S-R) terbutaline tablets (b.i.d. 0.25 mg/kg per day) and S-R theophylline (5.31 mg/kg morning and 10.62 mg/kg evening) were compared in eleven patients with nocturnal asthma. On day seven of each treatment period, drug serum concentrations and peak expiratory flow (PEF) were measured every 2h over a 24-h period. During daytime, te...

objective the goal of this study was to prepare and characterize alginate microspheres as an antigen delivery system and adjuvant for immunization against leishmaniasis. materials and methods microspheres were prepared by an emulsification technique and characterized for size, encapsulation efficiency, and release profile of encapsulates. selection of appropriate parameters (viscosity of algina...

the present study is aimed at the overall improvement in the efficacy, reduced toxicity and enhancement of therapeutic index of cisplatin. nanocapsules of cisplatin containing ethylcellulose have been prepared using solvent evaporation technique under ambient conditions. the prepared nanocapsules were used for controlled drug release of anticancer agents with gold and iron oxide nanoparticles. ...

Based on various characteristics of zeolite, its utilization in the manufacture of fertilizers with slow-release properties is possible. The objectives of this study are to characterize and utilized nitrogen, phosphorus and potassium (NPK) slow release fertilizer by using natural zeolite in Indonesia. In this research, zeolite was utilized as a mixture of Slow Release Fertilizer (SRF). Effect o...

the possibility of manufacturing and effects of a slow release non-protein nitrogen product on ruminant nutrition were evaluated in two separate experiments. in first experiment, making of slow release component was followed by connecting branched carbon chain to the molecule of urea to reduce the degree of solubility. then, the sample product was analyzed to assess its chemical structure, and ...