Aberrant expression of microRNAs (miRNAs), including miR-21, and alteration of their target genes stability have been associated with cellular transformation and tumorigenesis. We investigated the expression, regulation and function of miR-21 in leiomyomas which develop from myometrial cellular transformation. The results indicated that miR-21 is over-expressed in leiomyomas with specific eleva...

The accurate estimation of gridded daily precipitation is critical to hydrological modelling and water resource assessment. High resolution precipitation datasets based on gauge rainfall are the primary input to spatially distributed rainfall-runoff models and water balance calculations (e.g. Chiew et al., 2008). The spatial heterogeneity of rainfall variability is currently not captured adequa...

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introduction the knowledge about spatial variability of precipitation is a key issue for regionalization in hydro-climatic studies. measurements of meteorological parameters by the traditional methods require a dense rain gauge network. but, due to the topography and cost problems, it is not possible to create such a network in practice. in these cases the spatial distribution pattern of precip...

Remote sensing is an efficient means of obtaining largemeans to obtain these data in a timely and consistent manner. Yet, remotely sensed land-cover data are not errorarea land-cover data. Yet, remotely sensed data are not error-free. This paper presents a geostatistical method to free, as they rely largely on the spectral responses of landcover types that may not all be spectrally distinguisha...

Schlumpf et al. (1) reported on the in vitro and in vivo “estrogenicity” of six ultraviolet (UV) filters: benzophenone-3 (Bp-3), homosalate (HMS), 4-methyl-benzylidene camphor (4-MBC), octyl-methoxycinnamate (OMC), octyl-dimethyl PABA (OD-PABA), and butyl-methoxydibenzoylmethane (BMDM). The authors concluded that “UV screens should be tested for endocrine activity, in view of possible long-term...