BACKGROUND The shortage of autologous skin sources not only adds difficulty to the repair of extremely large-area deep burn wounds but affects the healing quality. The aim of the present study is to explore an ideal method for repairing large-areas burn wounds with low scar formation. METHODS Between 2002 and 2014, we used grafting of small auto- and cryopreserved allo-skin to repair large-ar...

BACKGROUND Burns are among the most devastating forms of injury. Nowadays the standard treatment for deep partial thickness and full-thickness burn is early excision and grafting, but this technique is not always feasible; and this leads to chronicity and microbial colonization of burn wounds. Interesting properties of human amniotic membrane made us use it in management of chronic infected bur...

Methods for handling burn wounds have changed in recent decades. Increasingly, aggressive surgical approach with early tangential excision and wound closure is being applied leading to improvement in mortality rates of burn victims. Autografts from uninjured skin remain the mainstay of treatment. Autologous skin graft, however, has limited availability and is associated with additional morbidit...

Burn injuries remain a significant cause of morbidity and mortality during modern military conflicts and peacekeeping operations. Considering that commercially available dressings are not designed to meet the challenges of treating combat burn wounds, DRDC Toronto has designed a novel, absorbent and medicated bi-layer wound dressing to address key requirements for treating external war wounds. ...

BACKGROND Burn wound infections carry considerable mortality and morbidity amongst burn injury victims who have been successfully rescued through the initial resuscitation. This study assessed the prevalent microrganisms causing burn wound infections among hospitalized patients; their susceptibility pattern to commonly used antibiotics; and the frequency of infections with respect to the durati...

The transport of cefmenoxime,a cephalosporin antibiotic,into three kinds of exudates (exudate from excoriated skin,exudate from burn wounds,and burn blister fluid)from blood was studied on 37 burn patients after they were given an intravenous bolus of 50mg cefmenoxime per kg body weight.Concentrations of cefmenoxime in serum and in the above exudates or fluid were determined by bioassay.Concent...

Intact human skin surface is essential for protection against infection, preservation of body fluid homeostasis and thermoregulation. Burn injury compromises the skin barrier and enables bacterial infection, hence delaying burn wound healing. This study aimed to determine the microbial profile of burn wounds, and resistance patterns of microbes with respect to the source of the injured patient'...

Hypergranulation tissue (or also known as overgranulation) may negatively influence burn wound healing time and contribute to recurrence of contractures in burn wounds and grafts. Subsequently, the treatment of hypergranulation tissue remains controversial and problematic. In this case series, we aimed to examine the feasibility and document the use of topical hydrocortisone in the treatment of...

background: burns are among the most common traumas in developing countries, which consume large amounts of medical resources. it is important to find an appropriate material for dressing of burn wounds that improves healing and is readily available, easily applicable, and economical.   methods: in a single-blind randomized controlled clinical trial from march to october 2006, 211 patients with...