نتایج جستجو برای: single nucleotide
تعداد نتایج: 949916 فیلتر نتایج به سال:
background the association between her2 ile655val single nucleotide polymorphism and cancer is controversial. objectives the aim of our study was to investigate this polymorphism in patients with ovarian cancer. patients and methods genomic dna was extracted from peripheral blood leukocytes of 107 patients and 130 healthy women. her2 gene polymorphism was assessed by pcr-rflp. results no signif...
objectives the aim of this study was to explore the association between axin2 gene polymorphism and papillary thyroid carcinoma (ptc). patients and methods 106 blood samples (56 ptc patients and 50 healthy controls) were drawn from china-japan :union: hospital in jilin province, china, during october 2010 to march 2011. a case-control study was designed to examine the association between axin2 ...
background: despite extensive progress in ivf techniques, one of the most difficult problems is the variability in the response to controlled ovarian hyperstimulation (coh). recent studies show the effects of individual genetic variability on coh outcome. objective: to evaluate the correlation between lhβ g1502a polymorphisms in exon 3 of the lh gene and ovarian response to coh. materials and m...
results no significant difference was found between the groups regarding bmht rs3797546 gene polymorphism. the c allele was not associated with ns-cl/p (or = 1.27, 95% ci = 0.85-2.79, p = 0.690). conclusions our data suggested that bmht rs3797546 gene polymorphism was not associated with risk/ protection for ns-cl/p in a sample of iranian population. larger studies are required to validate our ...
background hepatitis b virus (hbv) infection is a serious public health problem in china and worldwide. mother-to-child transmission is one of hbv’s main transmission routes in highly endemic regions. genome-wide association studies (gwas) identify single nucleotide polymorphisms (snps) at hla loci as associated with hbv infection. however, the mechanisms of hbv perinatal transmission and break...
objective(s):organic anion transporter polypeptide 1b1 (oatp1b1) encoded by solute carrier organic transporter 1b1 (slco1b1) gene; a transporter involved in the uptake of drugs and endogenous compounds is present in hepatocyte sinusoidal membrane. aim of this study was to investigate the frequencies of functionally significant snps (388a>g and 521t>c) and their haplotypes in 6 ethnic groups of ...
conclusions rs1595065 could be recommended as a risk factor in regulating her4 expression and affecting her2 positivity incidence among bc patients. methods overall, 156 patients and controls were genotyped using rflp-pcr. armitage test for trend was utilized to investigate the association between rs1595065 and susceptibility to bc. the possible change in the interaction between rs1595065 and m...
in the present research, molecular detection of bovine leukocyte adhesion deficiency (blad) and complex vertebral malformation (cvm)in a population of iranian holstein cows has been carried outusing milk somatic cells by polymerase chain reaction-restriction fragment length polymorphism(pcr-rflp). the blad and cvm are monogenic and autosomal recessive heredity lethal syndrome in holstein-friesi...
conventional methods for fungal identification in the clinical laboratory rely on morphological andphysiological tests. these tests often need several days or weeks to complete and are frequentlyunspecific. molecular identification mostly implies sequencing, which is relatively expensive andtime-consuming, as well as impractical for large numbers of isolates. the rolling circleamplification app...
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