The pathogen group A Streptococcus (GAS) produces a wide spectrum of infections including necrotizing fasciitis (NF). Streptolysin S (SLS) produces the hallmark beta-haemolytic phenotype produced by GAS. The nine-gene GAS locus (sagA-sagI) resembling a bacteriocin biosynthetic operon is necessary and sufficient for SLS production. Using precise, in-frame allelic exchange mutagenesis and single-...

PURPOSE To investigate the correlation between single limb support (SLS) phase (% of gait cycle) and the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) questionnaire and Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36 Health Survey) in patients with knee osteoarthritis (OA). METHOD A prospective observational study was employed with 125 adults with bilater...

We performed single-voxel proton MR spectroscopy (1H-MRS) in two children with Sjögren-Larsson's syndrome (SLS). Both patients showed two abnormal spectral peaks at 1.3 ppm and 0.9 ppm that were obtained with short echo times. These two abnormal spectral peaks were seen in high-intensity areas on T2-weighted images and also in basal ganglia of normal intensities. 1H-MRS may be useful for establ...

BACKGROUND Regular exercise training is one of the core components of multifactorial fall-prevention programs. OBJECTIVE To compare the effect of Tai Chi and combined exercise prescription that consists of three main components of an exercise prescription on static balance, dynamic balance, fear of falling and mood. METHODS Sixty older adults aged 55-76 were randomly assigned to Group 1 (Ta...

Many stochastic local search (SLS) methods rely on the manipulation of single solutions at each of the search steps. Examples are iterative improvement, iterated local search, simulated annealing, variable neighborhood search, and iterated greedy. These SLS methods are the basis of many state-of-the-art algorithms for hard combinatorial optimization problems. Often, several of these SLS methods...

As the latest extension of MPEG-4 Audio coding, MPEG-4 Lossless Audio Coding includes a scalable audio coding solution (SLS) that integrates the functionalities of lossless audio coding, perceptual audio coding, and fine granular scalable audio coding into a single coder framework while providing backward compatibility to MPEG Advanced Audio Coding (AAC) at the bit-stream level. Despite its abu...

INTRODUCTION Popliteal artery aneurysms (PAA) are rare. Different surgical techniques for open surgical repair are possible. This study presents a single centre experience using open surgical repair with a medial approach (MA) and outlines differences between symptomatic (SLS) and asymptomatic (ALS) legs. METHODS Data collection was performed retrospectively. The investigation period was from...

Normalization of electromyographic (EMG) amplitudes is necessary in the study of human motion. However, there is a lack of agreement on the most reliable and appropriate normalization method. This study evaluated the reliability of single leg stance (SLS) and maximal voluntary isometric contraction (MVIC) normalization methods and the relationship between these measures for the gluteus maximus ...

We tested the hypotheses that 1) a decrease in activation of skeletal muscles at short sarcomere lengths (SLs) is caused by an inhibition of Ca(2+) release from the sarcoplasmic reticulum (SR), and 2) the decrease in Ca(2+) would be caused by an inhibition of action potential conduction from the periphery to the core of the fibers. Intact, single fibers dissected from the flexor digitorum brevi...

OBJECTIVE To investigate the correlations of scores on the Timed Up and Go (TUG) test and the Single Leg Stance (SLS) test with stability scores on the Biodex Balance System (BBS) in healthy adults. METHOD The postural balance of 73 participants was measured on the TUG and SLS tests and with the Overall Stability Index (OSI) on the BBS. The participants were divided into groups by age and by ...