Because of the importance of microbial metabolites of cholesterol as precursors in the synthesis of steroidal drugs, we decided to study the ability of Arthrobacter simplex to degrade cholesterol. Arthrobacter simplex cleaves the side chain of cholesterol in the presence of 2,2'-dipyridyl and produces 4-androstene-3,17- dione (AD) and androsta- 1,4-diene-3,17-dione(ADD). Two other intermedi...

because of the importance of microbial metabolites of cholesterol as precursors in the synthesis of steroidal drugs, we decided to study the ability of arthrobacter simplex to degrade cholesterol. arthrobacter simplex cleaves the side chain of cholesterol in the presence of 2,2'-dipyridyl and produces 4-androstene-3,17- dione (ad) and androsta- 1,4-diene-3,17-dione(add). two other intermed...

the present case report introduces a patient with fluent aphasia, anterograde amnesia and anosmia due to herpes simplex encephalitis after her first delivery. the left medial temporal lobe was one of the main areas involved. on aphasia testing she showed severe anomia on both confrontation and free recall, agraphia, alexia, repetition disorder and some auditory comprehension impairments. therap...

conclusions herpes simplex virus was present in more patients with ms than healthy cases. hsv may be directly or indirectly associated with ms development. further comprehensive molecular studies are needed to confirm the etiopathologic association between hsv and ms disease. results totally, 63 (76.8%) patients with ms showed a history of hsv exposure by anti-hsv testing compared to 70 (78.7%)...

background :wide distribution and low half-life of acyclovir has led to a high dose consumption of the drug. recent studies have shown that encapsulation of acyclovir in nano-carriers can increase effectiveness and decrease its side effects. we investigated the inhibitory effect of acyclovir loaded nano-niosomes against herpes simplex virus type-1 (hsv-1) in cell culture.   methods : in-vitro c...

there are two interesting methods, in the literature, for solving fuzzy linear programming problems in which the elements of coefficient matrix of the constraints are represented by real numbers and rest of the parameters are represented by symmetric trapezoidal fuzzy numbers. the first method, named as fuzzy primal simplex method, assumes an initial primal basic feasible solution is at hand. t...

In this paper a hybrid algorithm based on exploration power of the Genetic algorithms and exploitation capability of Nelder Mead simplex is presented for global optimization of multi-variable functions. Some modifications are imposed on genetic algorithm to improve its capability and efficiency while being hybridized with Simplex method. Benchmark test examples of structural optimization with a...

objective herpes simplex virus (hsv), one of the most common sexually transmitted disease is a worldwide .this study aimed to prevalence of herpes simplex virus of pregnancy in iran. methods: we searched pubmed, scopus, ovid, science direct and national databases were searched: magiran, iranmedex and science information database (sid) up to october 2015.eventually, we included five studies that...

In this paper, an efficient extension of network simplex algorithm is presented. In static scheduling problem, where there is no change in situation, the challenge is that the large problems can be solved in a short time. In this paper, the Static Scheduling problem of Automated Guided Vehicles in container terminal is solved by Network Simplex Algorithm (NSA) and NSA+, which extended the stand...