In this study, the process of separating and analyzing oils from some plant seeds such as Washingtonia tree Silybum marianum(kulgan) Soxhlat apparatus was used in extraction process, where performed using organic solvents (Hexane Petroleum ether). Then appreciation percentage oil these plants. It found that marianum contain a higher than tree. Then, active functional groups were identified (FT-...

In order to respond to the basic requirements of food and pharmaceutical industries, to reduce or eliminate organic solvent residues in the final products, several extraction techniques were tested from the standpoint of performance, with low energy consumption. The aim of this study was to determine biological activities such as antioxidant and antiproliferative activities of flavonolignans fr...

Purpose: To develop a nanosuspension drug delivery system to enhance the dissolution rate of Silybum marianum seeds extract.
 Methods: Central composite design was used study effect input variables (stabilizer plant extract ratio, antisolvent solvent stirring time) on dependent (mean particle size, polydispersity index (PDI) and zeta potential). The optimized formulation characterized by S...

The effect of new synthetic pyrazinecarboxamide derivatives as potential elicitors of flavonolignan and flavonoid production in Silybum marianum and Ononis arvensis cultures in vitro was investigated. Both tested elicitors increased the production of flavonolignans in S. marianum callus and suspension cultures and flavonoids in O. arvensis callus and suspension cultures. Compound I, 5-(2-hydrox...

Deve dikeni (Silybum marianum) tohumuna çözücü ile ekstraksiyon yöntemi uygulanarak %7,3 verimle silimarin tozu elde edilmiştir. Ekstrakte tozun %57,8 içerdiği bulunmuştur. Silimarin içeriği dikkate alınarak silybum marianum tohumunun %4,21 olarak Ekstrakt ve orjinal silimarin, Fourier dönüşümlü kızıl ötesi spektroskopisi (FTIR), Optik Mikroskop, X-ışını kırınımı (XRD) taramalı elektron mikrosk...

Silybum marianum or milk thistle (MT) is the most well-researched plant in the treatment of liver disease. The active complex of MT is a lipophilic extract from the seeds of the plant and is composed of three isomer flavonolignans (silybin, silydianin, and silychristin) collectively known as silymarin. Silybin is a component with the greatest degree of biological activity and makes up 50% to 70...

introduction due to scarcity of forage and water resources and high feed prices in iran, it seems that the utilization of native and cheap forage resources for ruminants is important. the milk thistle (silybum marianum) is distributed in different regions of iran included: gonbad kavoos, gorgan, nodeh kalardasht, dareh hezareh, dasht mugan, poshtkoh, mollassani, shush, hamidieh, ramhormuz, izeh...

The paper presents the antioxidant activity evaluation of Silybum marianum L. extract in comparison with the commercial silymarin standard solution (2 mg/mL) and the time-dependent antioxidant capacity by calculating the free radical 2,2-diphenyl-1-pycryl-hydrazyl (DPPH) reaction rate in the presence of these biosystems. The best result was obtained in the case of S. marianum L. extract, with a...