OBJECTIVE Silicosis is usually recognized at later stages of the disease, and early biomarkers for silicosis will be useful for timely diagnosis. We aimed at examining plasma levels of TNF-α and MMP-9, and correlation between these, in patients with different stages of silicosis in order to test suitability of these inflammatory factors as early biomarkers for silicosis. PATIENTS AND METHODS ...

Abstract Background Silicosis is a progressive pneumoconiosis characterized by interstitial fibrosis following exposure to silica dust. The role of metabolic dysregulation in the pathogenesis silicosis has not been investigated detail. This study aimed identify different features plasma patients with and dust-exposed workers without metabolomics studies. Methods Patients silicosis, (DEWs) age-m...

Silicosis is an occupational lung disease caused by inhalation of crystalline silica. People working in occupations like sandblasting, surface drilling, tunneling, silica flour milling, ceramic making, and so forth are predisposed to develop silicosis. Crystalline forms of silica are more fibrogenic than the amorphous forms, highlighting the importance of the physical form in pathogenesis. Lung...

silicosis is considered to be among the occupational lung diseases and associated with sandblasting, mining, quarrying and tunneling. acute silicosis is usually progressive diseaseand despite treatment with corticosteroids it leads to cardio-respiratory failure and death. alveolar silicoproteinosis is one of it’s acute presentations due to exposure to silica dust and lungs filling with proteina...

Introducción: la silicosis, enfermedad crónica, causada por inhalación de polvo sílice cristalina, sigue siendo un problema salud laboral vigente. El objetivo investigación consistió en estimar el riesgo silicosis complicada y/o acelerada trabajadores expuestos a conglomerados cuarzo frente al los roca ornamental.
 Método: se desarrolló estudio analítico casos y controles prevalentes cuya ...

Silicosis may be defined as the disease resulting from chronic occupational exposure to silica dust. Silica is primarily composed of quartz dust and has been classified since 2000 as a known human carcinogen by the U.S. government. Silicosis may lead to impairment of lung function resulting from fibrosis of the lungs. This may in turn lead to an increased susceptibility to the development of tu...

Issuing fitness certificates to South African mine workers with early and mild silicosis continue risk work underground is a public health concern. This article draws on the view of solidarity contend this practice. We employed normative ethics approach concept in ‘Ubuntu’ philosophy report reflect implications silica dust exposure among miners. argued that since irreversible, incurable, could ...

Silicosis in enamel workers has been reported by Gaubatz (1940), Bruce (1945), Meures and Graf (1949), and Troisi (1952). One of Bruce's cases had third-stage silicosis (International Labour Office, 1930) and was completely disabled. A search of the literature, however, has revealed no further reports of advanced silicosis in such workers, even after long exposure to enamel dust. The cases desc...

BACKGROUND Epidemiological evaluations of the risk of silicosis in relation to exposure to crystalline silica have raised the question of whether different types of silica dust exposures vary with respect to their ability to cause silicosis. The aim of this study is to compare the risk of silicosis among cohorts of silica dust-exposed Chinese tin miners, tungsten miners, and pottery workers and...