We present experiments involving cancer cells adhering in microchannels, subjected to increasing shear stresses (0.1Pa to 30Pa). Morphological studies are carried out at different shear stresses. Cells exhibit spreading patterns similar to the ones observed in static conditions, as long as the shear stress is not too high. At critical wall shear stresses (around 2− 5Pa), cells decrease their ce...

Hard sphere colloidal particles are a basic model system for general research into phase behavior, ordering and out-equilibrium glass transitions. Experimentally it has been shown that oscillatory shearing of a monodisperse hard sphere glass, produces two different crystal orientations; a Face Centered Cubic (FCC) crystal with the close packed direction parallel to shear at high strains and an ...

The motion of an edge dislocation is analyzed for temperatures ranging from 10 K to 200 K and for stresses up to 5 GPa. The dislocation velocity versus the applied shear stress curve can be divided into four regimes corresponding to successively higher shear stresses. In the first regime, the applied shear stress is below the Peierls stress and the dislocation velocity is nominally zero. In the...

Brownian dynamics simulations of bidisperse hard discs moving in two dimensions in a given steady and homogeneous shear flow are presented close to and above the glass transition density. The stationary structure functions and stresses of shear-melted glass are compared quantitatively to parameter-free numerical calculations of monodisperse hard discs using mode coupling theory within the integ...

Using the infinitesimal theory of elasticity and analytical formulation, displacements and stresses based on the high-order shear deformation theory (HSDT) is presented for axisymmetric thick-walled cylinders made of functionally graded materials under internal and/or external uniform pressure. The material is assumed to be isotropic heterogeneous with constant Poisson’s ratio and radially varyi...

We examined the mechanisms used by eosinophils to tether and accumulate on interleukin-4 (IL-4)-stimulated human umbilical vein endothelial cells (HUVECs) under flow conditions. As previously reported, HUVECs treated for 24 hours with 20 ng/mL IL-4 had increased expression of P-selectin and vascular cell adhesion molecule-1 (VCAM-1) but not E-selectin. We found that eosinophils tethered and rol...

We examined the mechanisms used by eosinophils to tether and accumulate on interleukin-4 (IL-4)–stimulated human umbilical vein endothelial cells (HUVECs) under flow conditions. As previously reported, HUVECs treated for 24 hours with 20 ng/mL IL-4 had increased expression of P-selectin and vascular cell adhesion molecule-1 (VCAM-1) but not E-selectin. We found that eosinophils tethered and rol...

In this paper, a numerical solution has been developed for hollow circular cylinders made up of orthotropic material which is subjected to twist using micro polar theory. The effect of twisting moment and material internal length on hollow thick-walled circular cylinder made up of micro polar orthotropic material is investigated. Finite difference method has been used to exhibit the influence o...

Gels formed by semiflexible fibers such as most biopolymers exhibit non-linear behavior in their response to shear deformation, e.g., with a pronounced strain stiffening and negative normal stress. These negative normal stresses suggest that networks would collapse axially when subject to shear stress. This coupling of axial and shear deformations can have particularly important consequences fo...

It has been pointed out by some researchers that road pavements are subjected to vertical stress due to vehicles on them as well as shear stress at the time of braking or acceleration of vehicles. In this paper, the results of elastic analysis to obtain the rigorous solution for an elastic two-layer system subjected to surface shear stress are described and it is shown that the effect of shear ...