In the present study, the aqueous extract of Vigna unguiculata (L) Walp seed was evaluated for its hepatoprotective effect on etahnol induced acute liver damage on Wistar albino rats. The degree of protection was measured by using biochemical parameters such as serum glutamate oxalate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP), total bilirubin ...

Serum aspartate transaminase changes following open-heart surgery with ischaemic arrest (with and without coronary artery perfusion) Patients with aortic disease irrespective of whether they had coronary perfusion or not showed a significant difference in the level of postoperative SGOT levels compared with other groups. Aortics with coronary perfusion did not show a correlation between SGOT le...

SUMMARY The SGOT/SGPT ratio has been estimated in 207 patients with alcoholic liver disease and in 3 control groups (43 viral hepatitis, 30 non-alcoholic chronic liver disease and 42 obstructive jaundice). The SGOT/SGTP ratio in alcoholic liver disease group was significantly higher (2.6 3 '± 1.82) than in any of the 3 control groups. If we consider the different alcoholic liver diseases the ra...

objective(s):  there is a rising use of gold nanoparticles (aunps) in goods and in the medical fields but there is concern about the toxicity of them. so in this study spherical aunps with 3 different concentrations were applied for investigating their effects in vivo.   materials and methods:  40 male albino mice were randomly divided into sham, control, 25 ppm, 50 ppm, 100 ppm groups and were...

The incidence of INH-associated liver injury was evaluated in 239 children aged between 9 and 14 years, who were receiving 300 mg INH/day for tuberculosis prophylaxis. Serum SGOT and SGPT levels were determined before INH administration and at 4-weekly intervals thereafter. Levels of both enzymes were raised during the first 3 months of treatment in 18 (7.5%) children, while in 23 (9.6%) childr...

Hedyotis corymbosa Linn is spreading, suffruticose annual, belongs to family Rubiaceae frequently met with in field through out India, usually during rainy season. This plant is used for their medicinal properties as a folk medicine to treat jaundice, mouth wash in toothache. Hence the present study was aimed to investigate the hepatoprotective activity of ethanolic extract of Hedyotis corymbos...

Background: Little information is available on the trend in cardiovascular risk factors and hepatic enzymes in Iranian seafarers. The present study aimed at assessing the pattern of obesity, hypertension, diabetes, elevated serum glutamic oxaloacetate transaminase (SGOT), and serum glutamate pyruvate transaminase (SGPT) in Iranian seafarers during 2010 to 2014. Methods: Data on cardiovascular r...

Serum activity of SGOT, SGPT, LDH, and alkaline phosphatase was measured in 614 Michigan adults exposed to PBB and 141 Wisconsin adults not so exposed. The Michigan group had higher prevalence of abnormal SGOT (p less than 0.005) and SGPT (p less than 0.005). A clear sex difference was observed. Michigan men had a higher prevalence of abnormal SGPT (p less than 0.005) and LDH (p less than 0.005...

Serum glutamate oxaloacetate transaminase (SGOT), glutamate pyruvate transaminase (SGPT) and lactate dehydrogenase (LDH) activities increased significantly in rats restrained (RS) for 1 hour and exposed to force swimming exercise (FS) for 15min after an interval of 4 h thereby indicating tissue damage due to stress. The results further reveal that after initial stress exposure rats do respond t...