Difficulties in establishing the value of certain treatments for head injury are reviewed. An analysis of 1000 severely head injured patients, managed by varying methods in three different countries, showed that certain treatments were more often used in the most severely injured patients. Even when the severity of injury was taken account of, it appeared that the use of steroids and tracheosto...

Background: The pharmacodynamic differences in time to onset and dissipation of effect of sufentanil, fentanyl, and alfentanil probably result from different rates of blood-brain equilibration. The authors investigated this hypothesis in humans. Methods: After simultaneous central venous bolus application of sufentanil (10 pg), fentanyl (100 pg), and alfentanil (1,000 pg), arterial and jugular ...

traumatic brain injury is a leading cause of death in developed countries. it is estimated that only in the united states about 100,000 people die annually in parallel among the survivors there is a significant number of people with disabilities with significant costs for the health system. it has been determined that after moderate and severe traumatic injury, brain parenchyma is affected by m...

air in the intracranial vascular compartment is rare and only few case reports are published in the literature. without surgery or open head trauma, the origin of air bubbles in the venous sinus is still debated. we report an admitted patient in the emergency room one hour after a severe closed head injury, and in whom, the post-surgical cranial ct scan demonstrated feature of air embolism alon...

BACKGROUND Head injury is the major cause of death in a neurosurgical patient. OBJECTIVE To find the outcome, and treatment modality affecting the outcome in patients with head injury. METHODS Nine hundred eighty seven patients presenting to National Institute of Neurological and Allied Sciences, Kathmandu, with head injury from September 2009 to October 2010 were included in the study. Pat...

BACKGROUND Case fatality rates after all types of blunt injury have not improved since 1994 in England and Wales, possibly because not all patients with severe head injury are treated in a neurosurgical centre. Our aims were to investigate the case fatality trends in major trauma patients with and without head injury, and to establish the effect of neurosurgical care on mortality after severe h...

minor trauma to the head is common in childhood and does not require any medical or surgical treatment. nevertheless, head injury in infancy and childhood is the single most common cause of death and permanent disability. measurable deficits occur even after mild to moderate head injury but are markedly greater after severe injury. they include impaired cognition, motor impairments, disruption ...