نتایج جستجو برای: severe combined immunodeficiency

تعداد نتایج: 782574  

2003
Rebecca H. Buckley Daniel A. Ozaki Shui Cao Scott Langdon Marcella Sarzotti Dhavalkumar D. Patel Xiaojing Li Roberta E. Parrott Katherine Coyne

2002
Genoveffa Franchini Barbara K. Felber James Tartaglia George N. Pavlakis David C. Montefiori Zdenek Hel Janos Nacsa Elzbieta Tryniszewska Wen-Po Tsai Robyn Washington Parks

Journal: :The Journal of Experimental Medicine 2002
Philippe Poussier Terri Ning Diponkar Banerjee Michael Julius

Lymphocytes residing in the intestinal epithelium are exclusively T cells and account for one of the largest collection of T cells in the organism. However, their function remains obscure. We and others have shown that the development of intestinal intraepithelial T cells is compromised in mutant mice prone to chronic intestinal inflammation. These results led us to directly assess their role i...

Journal: :Antimicrobial agents and chemotherapy 2001
D G Wolf I Yaniv S Ashkenazi A Honigman

Infection with multiple ganciclovir-resistant human cytomegalovirus mutants, containing different substitutions and deletions in the UL97 gene, was found in a patient with severe combined immunodeficiency (SCID) within 3 weeks of ganciclovir therapy. A novel 11-codon deletion at positions 590 to 600 was identified. These unique findings may be related to the nature of the immunodeficiency in th...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001
A Nowak-Wegrzyn W Phipatanakul J A Winkelstein M S Forman H M Lederman

Two patients with severe combined immunodeficiency and enterovirus infections were successfully treated with pleconaril. There were no adverse affects.

2007
Louise Lund Lina Jönsson Susanne Eriksson

Severe Combined Immunodeficiency (SCID) is a disease with a genetic background in Arabian horses and crossbreeds with Arabians. The disease has been known and documented since the 1970’s and was early suggested to have an autosomal recessive mode of inheritance. Foals that are affected with SCID lack production of both B and T lymphocytes and consequently die from secondary diseases within a sh...

Journal: :Archives of disease in childhood 1997
C M Cale N J Klein V Novelli P Veys A M Jones G Morgan

Children presenting with disseminated viral infections should be carefully investigated because they almost invariably have an underlying immunodeficiency. A child is reported who had disseminated cytomegalovirus and a novel form of severe combined immunodeficiency with abnormal expression of the common leucocyte antigen, CD45.

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2000
P Bousso V Wahn I Douagi G Horneff C Pannetier F Le Deist F Zepp T Niehues P Kourilsky A Fischer G de Saint Basile

In this report, we have analyzed the human T cell repertoire derived in vivo from a single T cell precursor. A unique case of X-linked severe combined immunodeficiency in which a reverse mutation occurred in an early T cell precursor was analyzed to this end. It was determined that at least 1,000 T cell clones with unique T cell receptor-beta sequences were generated from this precursor. This d...

Journal: :Japanese Journal of Clinical Immunology 2002

Journal: :Immunology and Allergy Clinics of North America 2010

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