background: il-17 is a major cytokine player in t cell mediated leukocyte associated inflammation. il-17 is also recognized to participate in the pathophysiology of asthma. objective: to determine the role of il-17 in predicting severe asthma. methods: we obtained serum samples from asthmatic children under the age of 5-year in three different groups of mild (n=33), moderate (n=28) and severe (...

asthma environmental triggers play important roles in severity of disease. passive smoking could exacerbate asthma symptoms and enhance the decrease in lung function. cotinine levels could be a reflection of passive exposure to the cigarette both in adults and pediatrics. the aim of this study was to determine degree of association of asthma severity and cotinine level as a marker of passive sm...

Background and Objective: Asthma is the most common chronic disease of childhood. The disease is caused by a temporary blockage of airflow due to chronic inflammation of the airways . One of the conditions that often occur with asthma and exacerbate disease, is gastroesophageal reflux. The aim of this study is to evaluate the role of acid suppressing therapy in patients with refractory asthma...

Severe asthma is defined as either refractory to traditional therapies or controlled only with that have intolerable side effects. Biological agents are known offer treatment alternatives patients type 2 inflammation severe asthma. We describe the case of a woman long history asthma, uncontrolled symptoms and need systemic corticosteroid therapy prevailing features, respiratory failure differen...

IntroductionChildren with severe asthma attack are a challenging group of patients who could be difficult to treat and leading to significant morbidity and mortality. Asthma attack severity is qualitatively estimated as mild, moderate and severe attacks and respiratory failure based on conditions such as respiration status, feeling of dyspnea, and the degree of unconsciousness. part of which ar...

Background: Asthma is the most common chronic disease of childhood. Exposure to allergens plays an important role in asthma. Recently, cockroach has attracted attentions as an important allergen. Objective: To evaluate cockroach allergy in Iranian children with asthma. Methods: 100 children with asthma were studied. After determination of asthma severity, serum total IgE and blood eosinophils w...

introductionchildren with severe asthma attack are a challenging group of patients who could be difficult to treat and leading to significant morbidity and mortality. asthma attack severity is qualitatively estimated as mild, moderate and severe attacks and respiratory failure based on conditions such as respiration status, feeling of dyspnea, and the degree of unconsciousness. part of which ar...