background: accurate and rapid assessment of allograft function is essential in renal transplant recipients in order to detect allograft rejection and to monitor drug nephrotoxicity. we aimed to evaluate the usefulness of cystatin c as a marker of kidney allograft function in the early post-transplant period and to compare this value with that of conventional serum creatinine concentration.   m...

conclusions the major finding of this study is that one unit increase in serum creatinine level suggests an increased risk of graft failure of up to four times. patients and methods this study was carried out at the department of nephrology, baqiyatallah hospital, baqiyatallah university, tehran, iran, between april 2005 and december 2008. during that time period, 461 patients who had undergone...

OBJECTIVE: Level of serum homocysteine is remarkably common among patients with moderate to sever renal failure. We assessed whether serum homocysteine concentrations were correlated with proteinuria in overt diabetic nephropathy. MATERIALS AND METHODS: A cross-sectional study was carried out on 45 patients (29 males, 16 females) with overt proteinuria. All subjects had type 2 diabetes. Data i...

Background: Accurate and rapid assessment of allograft function is essential in renal transplant recipients in order to detect allograft rejection and to monitor drug nephrotoxicity. We aimed to evaluate the usefulness of cystatin C as a marker of kidney allograft function in the early post-transplant period and to compare this value with that of conventional serum creatinine concentration. Met...

Objective: Diabetes mellitus is a multifactorial metabolic disorder that affects multiple organs of the body, one of the most important of which is chronic kidney disease. Early diagnosis of this disease is suggested as an important strategy to reduce the complications of the disease worldwide. Since the measurement of salivary creatinine and glucose is an easy and noninvasive method, the aim o...

Cystatin C is a 13 KD basic protein that is a member of the cystatin superfamily of cysteine protease inhibitors. The cystatin C gene seems to be a house keeping gene, which is compatible with a stable production rate of cystatin C by most cells. This protein is freely filtered through the glomerulus and almost completely reabsorbed and catabolized by proximal tubular cells. Because of the...