نتایج جستجو برای: serotonergic system
تعداد نتایج: 2235328 فیلتر نتایج به سال:
Purpose: The nucleus raphe magnus (NRM) is a medullary nucleus containing serotonergic and non serotonergic neurons, both of which densely project to spinal cord. The goal of this study was to determine the role of these non serotonergic neurons in pain perception and their cytological changes after the specific lesion of bulbo-spinal serotonergic pathway. Materials and Methods: Male rats were...
The endocannabinoid (eCB) system possesses neuromodulatory functions by influencing the release of various neurotransmitters, including γ-aminobutyric acid (GABA) and glutamate. A functional interaction between eCBs and the serotonergic system has already been suggested. Previously, we showed that cannabinoid type-1 (CB1) receptor mRNA and protein are localized in serotonergic neurons of the ra...
A common feature of arousing stimuli used as reinforcement in animal models of learning is that they promote memory formation through widespread effects in the central nervous system (CNS). In the marine mollusk Aplysia, sensitization is typically induced by tailshock, an aversive reinforcer that triggers a state of defensive arousal characterized by escape locomotion and increased heart rate. ...
In the brain, serotonin (5-hydroxytryptamine, 5-HT) controls a multitude of physiological and behavioral functions. Serotonergic neurons in the raphe nuclei give rise to a complex and extensive network of axonal projections throughout the whole brain. A major challenge in the analysis of these circuits is to understand how the serotonergic networks are linked to the numerous functions of this n...
The central serotonergic system is comprised of tryptophan hydroxylase-expressing neurons located in the raphe nuclei of the brain stem. Rostral groups of raphe serotonin neurons project throughout the forebrain, while caudal groups innervate the brain stem and spinal cord [1]. The serotonergic system modulates mood [2], anxiety [3], aggression [4], reward systems [5], and impulsivity [6], and ...
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