OBJECTIVES To examine the performance of the urinary biomarker panel tissue inhibitor of metalloproteinase-2 and insulin-like growth factor-binding protein 7 in patients with sepsis at ICU admission. To investigate the effect of nonrenal organ dysfunction on tissue inhibitor of metalloproteinase-2 and insulin-like growth factor-binding protein 7 in this population. METHOD In this ancillary an...

OBJECTIVES To reassess the prognosis of patients with cirrhosis admitted to the intensive care unit. DESIGN A retrospective study in a medical intensive care unit in a teaching hospital in France. PATIENTS All patients with cirrhosis without previous liver transplantation admitted in the period from 2005 to 2008. INTERVENTIONS None. MAIN RESULTS One hundred thirty-eight patients were st...

We studied anthrax immune globulin intravenous (AIG-IV) use from a 2009-2010 outbreak of Bacillus anthracis soft tissue infection in injection drug users in Scotland, UK, and we compared findings from 15 AIG-IV recipients with findings from 28 nonrecipients. Death rates did not differ significantly between recipients and nonrecipients (33% vs. 21%). However, whereas only 8 (27%) of 30 patients ...