Bisphenol-A (BPA) is a synthetic estrogen and monomer component of polycarbonate plastics and epoxy resins that are widely used in the production of food and beverage containers. It leaches into our food and drink at concentrations shown to have biological consequences. Here we show that exposure to low levels of BPA accelerated early embryonic development within 24h of exposure, attenuated bod...

The major product of the XLR (X-chromosomal, lymphocyte-regulated) locus is found to be a 30-kD nuclear protein with a relatively short (t1/2 approximately equal to 2 h) half-life. Together with its stage- and tissue-specific pattern of expression, this suggests a role for this protein in the regulation of differentiation in T and B lymphocytes. Interestingly, the XLR protein almost completely ...

P hysiologists and physicians have long been interested in blood flow and pressure (i.e., hemodynamics). The importance of the circulatory system in regulating health and disease has been appreciated since the days of blood-letting and leaches. In 1738, Daniel Bernoulli (1) elegantly described the impact of narrowings on pressure and flow in his book Hydrodynamica. The principles he described t...

Acidic deposition is comprised of sulfuric and nitric acids and ammonium derived from atmospheric emissions of sulfur dioxide, nitrogen oxides, and ammonia, respectively. Acidic deposition has altered soil through depletion of labile pools of nutrient cations (i.e. calcium, magnesium), accumulation of sulfur and nitrogen, and the mobilization of elevated concentrations of inorganic monomeric al...

Bisphenol A (BPA) is an endocrine-disrupting chemical that leaches from polycarbonate plastics that consequently leads to low-dose human exposure. In addition to its known xenoendocrine action, BPA exerts a wide variety of metabolic effects, but no data are available on its actions on the functions of liver mitochondrial. To assess these effects, HepG2 cells were exposed to BPA (10(-4)-10(-12)M...

thechah nimeh reservoirs of sistan is as one of the main water sources of zabol city used for drinking, agriculture, industry and livestock purposes. this study aimed to determine the contribution of the natural and concentration factors of heavy metals such as cd, pb and cu in sediment of chah nimeh of sistan. the concentrations of heavy metals in surface sediments were studied in six stations...

high quantity of chemical fertilizer use in farms to increase production but low efficiency irrigation leaches part of nitrate and follows groundwater pollution. in this research, extra water below root zone as deep percolation collected with point drains which installed interface of natural drainage zone and agricultural soil in university of tehran research farms. then, concentration of nitra...

we analyze a sequential decision making process, in which at each stepthe decision is made in two stages. in the rst stage a partially optimalaction is chosen, which allows the decision maker to learn how to improveit under the new environment. we show how inertia (cost of changing)may lead the process to converge to a routine where no further changesare made. we illustrate our scheme with som...