background: the sentinel lymph node (sln) is defined as the first chain node in the lymphatic basin that receives primary lymphatic flow. if the sln is negative for metastatic disease, then other nodes are expected to be disease-free. sln techniques have been extensively applied in the staging and treatment of many tumors, including melanoma, breast and vulvar cancers. this study aims to evalua...

introduction: sentinel lymph node biopsy is the standard procedure for lymph node staging in intermediate thickness melanoma. in iran, this procedure has not been addressed sufficiently. in this study, we report our experience in this area. methods: ten consecutive patients with intermediate thickness melanoma where included in our study. 1.5 mci of tc-99m antimony sulfide colloid in two divide...

background : sentinel lymph node biopsy is used as an accurate staging procedure to detect early breast cancer. several studies have documented that sentinel lymph node biopsy can accurately determine the status of axillary nodes. sentinel node biopsy offers the advantage of accurately staging the axilla and eliminating the need for a full axillary dissection for patients who have a negative se...

lymph node status remains an important prognostic indicator for survival in breast cancer. sentinel lymph node biopsy has become the standard method of assessment of clinically node negative breast cancers. economic implications as well as patient related factors have lead to the development a number of intra-operative techniques. review of the emerging trends in the last 4 years show that alth...

  Introduction: Sentinel lymph node biopsy is the standard procedure for lymph node staging in intermediate thickness melanoma. In Iran, this procedure has not been addressed sufficiently. In this study, we report our experience in this area. Methods: Ten consecutive patients with intermediate thickness melanoma where included in our study. 1.5 mCi of Tc-99m antimony...

introduction: there is a consensus in the literature that sentinel lymph node biopsy is the standard procedure for axillary staging in early stage (i and ii) breast cancer patients. usually during lymphoscintigraphy, the location of the sentinel lymph node is marked on the skin by an indelible ink. in this study we evaluated this issue in our patients. methods: 40 patients with the clinical dia...

background: the role of diagnostic pathology has become more prominent. this study aimed to compare the accuracy of frozen section compared with permanent section in the morning and afternoon working hours. methods: in this cross-sectional study, 99 patients with stage 1 and 2 breast cancer who underwent sentinel and non-sentinel lymph node biopsy between 2013 and 2015 were included. the result...

Background: Cervical cancer is the second most common type of cancer among women. Effective screening programs can help cancer detection in early phases and reduce death. Metastasis to lymph nodes is one of the most prognostic factors in patients who underwent surgery. Also, a positive result from pathology report alert oncologist as a cause of death. Sentinel lymph node biopsy has been widely ...

The initial tumor-draining lymph node, the sentinel lymph node, not only constitutes the first expected site of micrometastasis but also the first point of contact between tumor-associated antigens and the adaptive immune system. A tumor-induced decrease in the frequency and activation state of sentinel lymph node dendritic cells will impair the generation of effective antitumor T-cell response...

vulvar cancer is a rare gynecological malignancy with mainly lymphatic spread. sentinel node mapping plays an important role in the management of this gynecological malignancy. in the current study, we reported our experience in sentinel node mapping of vulvar cancer and review the literature accordingly. since the introduction of sentinel node mapping to the surgical oncology community of our ...