Objective. Unilateral sensory and motor blockade is known to occur with epidural anesthesia but is rarely reported in children. The differential diagnosis should include the presence of a midline epidural septum. Case Report. We describe a case of a 16-year-old adolescent who developed repeated complete unilateral extensive epidural sensory and motor blockade with Horner's syndrome after thorac...

conclusions it seems that tertiary amine drugs such as amitriptyline and doxepin had reasonable potencies of spinal blockade when compared to bupivacaine. however, amitriptyline had a more potent and long-acting spinal anesthetic effect. amitriptyline may turn out to be a clinically valuable local anesthetic. results in groups 1 and 2, a total of 3 rats died. after adjusting the concentrations,...

Sensory-selective local anesthesia has long been a key goal in local anesthetic development. For example, it allows women to be pain-free during labor without compromising their ability to push. Here we show that prolonged sensory-selective nerve block can be produced by specific concentrations of surfactants-such as are used to enhance drug flux across skin-in combination with QX-314, a lidoca...

INTRODUCTION The aim of the study was to compare the sensory, motor, and neuroophthalmological effects of isobaric levobupivacaine and bupivacaine when intrathecally administered. MATERIALS AND METHODS A prospective, double-blind, randomized study with 60 ASA grade I-II patients aged 18-65 years awaiting knee arthroscopy under spinal anesthesia. Patients received 12.5 mg of isobaric bupivacai...

Six volunteers underwent i.v. regional anaesthesia on two occasions using 0.5% prilocaine 40 ml with potassium 0 or 4 mmol litre-1. Addition of potassium produced more rapid sensory blockade to pinprick at five of the six sites tested, although this was statistically significant at only one site (P less than 0.05) and more rapid sensory blockade to pinch with Allis forceps at four of the six si...

BACKGROUND Extension of sensory blockade after an epidural top-up in combined spinal epidural (CSE) anesthesia is partly attributed to compression of the dural sac by the injected volume. This study investigated whether a volume effect plays a significant role when administering an epidural top-up after an initial epidural loading dose and assessed the predictive value of different factors with...

conclusions the addition of tramadol to epidural 2% lidocaine offers advantages in cesarean section. results in the lt100 group, onset of complete sensory and motor blockade at t6 was less than in the two other groups, but the highest level of sensory blockade and two segment regression and duration of motor blockades between the lt50 and lt100 groups were not significantly different, although ...

Background: Several clinical studies have shown that clonidine prolongs sensory motor blockade when used with bupivacaine but ideal doses of clonidine on ropivacaine is not well defined and to evaluate the effect of two doses of clonidine on ropivacaine, for supraclavicular brachial plexus blockade. Methods: In a prospective randomized double blind study supraclavicular brachial plexus blockade...

Background The rationale for injection of epidural medications through the needle is to promote sooner onset of pain relief relative to dosing through the epidural catheter given that needle injection can be performed immediately after successful location of the epidural space. Some evidence indicates that dosing medications through the epidural needle results in faster onset and improved quali...