BACKGROUND This study was to compare the effect of a stimulant laxative alone and in combination with traditional Japanese medicine Daikenchuto (TJ-100) in improving stool frequency and in alleviating bloating and abdominal pain in patients with chronic constipation. METHODS Twenty-two patients with chronic constipation who required sennoside (24 - 60 mg daily) were allocated to two groups fo...

(2) Sennoside B R S which impart strong laxative properties. Although, a number of synthetic laxatives are available, sennoside-containing preparations are still the most widely used (Atzorn et al., 1981). C. angustifolia is cultivated extensively in the Ram Nath Puram district of Tamilnadu (Husain e f al., 1992). During our crop improvement programme a quick, sensitive and accurate analytical ...

Several poly-herbal formulations containing senna (Cassia angustifolia) leaves are available in the Indian market for the treatment of constipation. The purgative effect of senna is due to the presence of two unique hydroxy anthracene glycosides sennosides A and B. A HPTLC method for the quantitative analysis of sennosides A and B present in the formulation has been developed. Methanol extract ...

BACKGROUND/AIM Even though polyethylene glycol-electrolyte lavage (PEG-EL)-based regimes have become the gold standard in recent years, to finish drinking 4 L of PEG-EL solution can be difficult. The quality of sennoside-based bowel-cleansing regimes used in Turkey has been known for some time. Therefore, we aimed to investigate the efficacy of both bowel-cleansing regimes. MATERIALS AND METH...

Rhizoma Rhei, cortex Magnoliae Officinalis and fructus Aurantii Immaturus compose dachengqi tang (DCQT), a classical formula of traditional Chinese medicine (TCM) that is used for acute intestinal obstruction and has been proven to be effective and economic. However, the ingredients of TCM are complicated, and it is unclear which ingredients are the most important for its effects. In this paper...

A calcium sennoside was extracted by developed microwave assisted extraction technique from Senna leaves. Microwave extraction was carried out at 250 W for 20 minutes, 350 W for 15 minutes and 450 W for 10 min heating period, these produced increase yields of calcium sennosides when compared to conventional heating. The yield of calcium sennosides obtained by microwave extraction was found to b...

A method fbr high-perfbrmance liquid chromatography (HPLC) has been estahlished fbr the simultaneous determination of rheinanthrone, sennidin A, scnnidin B and rhein formed by incubation f sennoside A with rat and mouse feces. The analysis was done within 20 min with a Wakosil-II5C18HG column by linear gradient elution using a mobile phase containing aqucous phosphoric acid and acetonitrile. Rh...