Due to its laxative effects, senna (Cassia angustifolia) has been used frequently in our country and the whole world. We aimed to present a case in which a probable hepatotoxicity and death occurred because of senna used in large quantities for a long time due to its laxative effects. A sixty years old female patient admitted our emergency service with the complaints of weakness, abdominal pain...

Objective- The aim of this study was to evaluate the efficacy and safety of senna as an alternative or adjunct to polyethylene glycol (PEG) solution in dogs using colonoscopy and radiography.Design - Experimental study.Animals - 20 adult mongrel healthy dogs.Procedures- Dogs were randomly allocated to receive 1 of 4 different bowel preparation regimens including PEG, senna or ...

Senna villosa (Miller) is a plant that grows in México. In traditional Mexican medicine, it is used topically to treat skin infections, pustules and eruptions and to heal wounds by scar formation. However, studies of its potential anti-inflammatory effects have not been performed. The aim of the present study was to determine the anti-inflammatory effect of extracts from the leaves of Senna vil...

BACKGROUND The aim of this study was to determine the efficacy of two methods of colon preparation for colon cleansing in a randomized controlled trial. METHODS In this prospective randomized investigator-blinded trial, consecutive outpatients indicated for elective colonoscopy were randomized into two groups. Patients in Senna group took 24 tablets of 11 mg Senna in two divided doses 24 hour...

The use of medicinal herbs to relieve and treat diseases is increasing because of their mild features and few side effects (Basgel and Erdemoglu, 2006). These plants are unlicensed and freely available, however, and there is no requirement to demonstrate efficacy, safety or quality (Ernst, 1998). Cassia angustifolia Vahl (Family: Caesalpinaceae), popularly known as senna, is a valuable plant dr...

OBJECTIVES Safety and effectiveness of large-volume polyethylene glycol-based solution (PEG-ES) have been documented, but the taste and volume can be barriers to successful colonoscopy preparation. Efficacy and safety of small-volume electrolyte-free (PEG-P) preparation (Miralax) for colonoscopy preparation have been rarely studied, although presently used at many pediatric centers. The primary...

Medicinal plants play an important role in the treatment of various illnesses in Kenya and the whole world. Senna didymobotya is one of such plants used traditionally in Kenya to treat illnesses such as diarrhea, malaria, ringworm, jaundice and intestinal worm. The main aim was to determine the acute toxicity of Senna didymobotya roots. The methanol total and dichloromethane crude root extracts...

The leaves of 10 Cassia species (Leguminosae), cultivated in Nigeria, were assayed spectrophotometrically for combined anthraquinone content and also pharmacologically for their laxative properties in male albino rats using official senna leaves (Cassia acutifolia Del.) as the reference standard. Leaves of C. podocarpa Guill, and Perr. and of senna had identical laxative potency. The results of...

Herbal medicine is widely used worldwide and is associated with side-effects such as skin eruptions. Herbal drugs are often produced by combining multiple crude drugs, mostly of plant origin. Determining which medi-cinal plants are associated with the herbal drugs that induce skin eruptions can therefore be difficult. This study investigated mRNA expression of several cytokines in peripheral mo...

Ethanolic extracts of Canarium schweinfurthii stem bark and Senna alata leaf, and aqueous extract of unripe Carica papaya fruit, at two different doses (150, 400 mg/kg), were evaluated for antihyperglycaemic and hypolipidemic effects on alloxan-induced diabetic rats following daily oral administration for 28 days. While antihyperglycaemic effect was lacking in Senna alata, it was persistent (P<...