To expand the potential of pseudopterosins and seco-pseudopterosins isolated from the octocoral Pseudopterogorgia elisabethae of San Andrés and Providencia islands (southwest Caribbean Sea), we report the anti-microbial profile against four pathogenic microorganisms (Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa and Candida albicans) and report a more complete cytotoxic p...

Minor products in the reaction between substituted 1,3-diiminoisoindolines and 2,5-diamino-3,4-dicyanothiophene were identified as the nickel seco-tribenzoporphyrazines 4 and 5, which have been characterized by UV-vis, MCD, NMR, and mass spectroscopy. Experimentally observed tetraazachlorin-type UV-vis spectra of new seco-tribenzoporphyrazines were explained on the basis of DFT and TDDFT calcul...

Thanks to the Web, access to an increasing wealth and variety of information has become near instantaneous. To make informed decisions, however, we often need to access data from many different sources and integrate different types of information. Manually collecting data from scores of web sites and combining that data remains a daunting task. The ERC projects SeCo (Search Computing) and DIADE...

Synthetic investigations towards the structurally complex and highly decorated framework of B-seco limonoid natural products by means of a [3,3]-sigmatropic rearrangement are described. Detailed model studies reveal, that an Ireland-Claisen rearrangement can be employed to construct the central C9-C10 bond thereby giving access to the B-seco limonoid scaffold. However, application of the develo...

The Semantic Web has motivated many communities to provide data in a machinereadable format. However, the available data has not been utilized to far to the extent possible. The data, which has been created by a large number of people, is dispersed across the Web. Creating the data without central coordination results in RDF of varying quality and makes it obligatory to cleanse the collected da...

Decandrinin (1), an unprecedented C9-spiro-fused 7,8-seco-ent-abietane, was obtained from the bark of an Indian mangrove, Ceriops decandra, collected in the estuary of Godavari, Andhra Pradesh. The constitution and the relative configuration of 1 were determined by HRMS (ESI) and extensive NMR investigations, and the absolute configuration by circular dichroism (CD) and optical-rotatory dispers...

Strengthening the Competitiveness of Export Oriented Agro Value Chains Cashew Nut Value Chain in Mozambique Date of submission: 31 January 2011 Region: Africa Country: Mozambique Type: Technical cooperation (building productive capacity) Author: Swiss State Secretariat for Economic Affairs (SECO) Contact Details: SECO, Economic Cooperation and Development: Hans‐Peter Egler, Head Trade Promoti...

The (seco)iridoids and their derivatives, the monoterpenoid indole alkaloids (MIAs), form two large families of plant-derived bioactive compounds with a wide spectrum of high-value pharmacological and insect-repellent activities. Vinblastine and vincristine, MIAs used as anticancer drugs, are produced by Catharanthus roseus in extremely low levels, leading to high market prices and poor availab...

Lignans are dietary diphenolic compounds which require activation by intestinal bacteria to exert possible beneficial health effects. The intestinal ecosystem plays a crucial role in lignan metabolism, but the organisms involved are poorly described. To characterize the bacterial communities responsible for secoisolariciresinol (SECO) activation, i.e., the communities that produce the enterolig...

Cloud storage services enable users to remotely store their data and eliminate excessive local installation of software and hardware. There is an increasing trend of outsourcing enterprise data to the cloud for efficient data storage and management. However, this introduces many new challenges toward data security. One critical issue is how to enable a secure data collaboration service includin...