tion, and the lipidized DF, with a homogeneous yellowish area.3,6 Although initially considered rare, sebaceous structures are identified in more than 15% of DFs,4,5,7 even in multiple forms.8 This finding is typical in lesions localized in the anatomical area of the shoulder (shoulder, proximal region of the arm, upper back and deltoid region), being observed in more than 40% of these cases, p...

tion, and the lipidized DF, with a homogeneous yellowish area.3,6 Although initially considered rare, sebaceous structures are identified in more than 15% of DFs,4,5,7 even in multiple forms.8 This finding is typical in lesions localized in the anatomical area of the shoulder (shoulder, proximal region of the arm, upper back and deltoid region), being observed in more than 40% of these cases, p...

AIMS Regulation of cell cycle progression is a fundamental control process, linked to cellular differentiation and apoptosis in normal tissues. p21(WAF1) is a nuclear protein that regulates cell cycle progression. p21(WAF1) can be transcriptionally upregulated by p53, but may be activated independently of p53-for example, during terminal differentiation. Loss of topological control of p21(WAF1)...

INTRODUCTION Superficial epithelioma with sebaceous differentiation is a rare benign epithelial neoplasm. It usually involves the head, neck or the back of a middle-age person. To the best of our knowledge, two ocular cases have been reported in the literature. CASE PRESENTATION A 46-year-old man of Italian descent, with a known history of testicular seminoma treated by orchiectomy with chemo...

Malignant cutaneous mixed tumor (CMT) is a very rare adnexal tumor with biphasic differentiation. In rare cases, a benign CMT (chondroid syringoma) undergoes malignant transformation. Sebaceous differentiation in a cutaneous malignant mixed tumor has not been previously reported. We present a malignant CMT with sebaceous differentiation, which occurred on the scalp of an 81-year-old man. The tu...

the primary feature of the mammalian skin includes the hair follicle, inter-follicular epidermis and the sebaceous glands, all of which form pilo-sebaceous units. the epidermal protective layer undergoes an ordered/programmed process of proliferation and differentiation, ultimately culminating in the formation of a cornified envelope consisting of enucleated corneocytes. these terminally differ...

Sebaceoma is a benign tumor with sebaceous differentiation. It usually presents as a yellowish papule or nodule on the face and scalp. This is a report of a 27-year-old-woman who presented with a giant, 6cm×4.5 cm exophytic tumor on her head. Clinically, we considered several diseases; however, the histological and immunohistochemical features matched those of sebaceoma. The lesion was excised ...