Dermatomycoses are very common infections caused mainly by dermatophytes. Scytalidiosis is a differential mycological diagnosis, especially in tropical and subtropical areas. Since a culture-based diagnosis takes 2 to 3 weeks, we set up a PCR-restriction fragment length polymorphism (RFLP) method for rapid discrimination of these fungi in clinical samples. The hypervariable V4 domain of the sma...

Fungal endophthalmitis after surgery or trauma is uncommon. 1-7 We are not aware of any report in the literature ofScytalidium dimidiatum (under the name S synanamorph subspecies of Hendersonula toruloidea) causing eye infection.>" This paper reports a severe case of S dimidiatum -endopthalmitis following trauma. Despite intraocular amphotericin B, miconazole, topical natamycin, and extensive s...

BACKGROUND: Scytalidium sp. is a fila men tous (thread-like), sapro bic fun gus which affects soil and plants. It is cur rently con si de red a pri mary patho gen of the nail. The pre va len ce of nail infec tions cau sed by this fun gus has been increa sing in recent deca des, although few publis hed stu dies have been done on its epi de mio logy. OBJECTIVE: To study cli ni co-epi de mio lo gi...

We cloned XYL1, a Scytalidium acidophilum gene encoding for an acidophilic family 11 xylanase. The XYL1p protein was expressed in Pichia pastoris using the pPICZalphaA expression plasmid. The secreted protein was purified by TAXI affinity column chromatography. The purified XYL1p showed an optimum activity at pH 3.2 and 56 degrees C. The Michaelis-Menten constants were determined.

More than thirty isolates of the thermophilic Torula-Humicola complex, mainly obtained from mushroom compost. were examined and compared with the available type cultures of Torula thermophila, Humicola grisea var. thermoidea and H. insolens. Scytalidium thermophilum is considered to be the correct name for all these isolates and type cultures, but the species is very variable in macroscopical a...

We previously showed that the females of the mushroom sciarid, Lycoriella ingenua (Dufour, 1839) (Diptera: Sciaridae), one of the most severe pests of the cultivated white button mushroom, Agaricus bisporus (J.E. Lange) Emil J. Imbach (Agaricales: Agaricaceae), are attracted to the mushroom compost that mushrooms are grown on and not to the mushrooms themselves. We also showed that females are ...

We describe a case of invasive fungal sinusitis caused by Scytalidium dimidiatum in a lung transplant recipient. Treatment was complicated by renal failure with amphotericin B therapies. Following 6 months of voriconazole treatment, the patient remained radiographically and clinically stable for a short time before dying of respiratory failure precipitated by graft rejection.

Scytalidium dimidiatum, a dematiaceous fungus, has been well established as an agent of dermatomycosis. There are few reports of invasive infection caused by S. dimidiatum; most infections occurred in immunocompromised hosts. We present an immunocompetent patient with pleural S. dimidiatum infection and review nine other published cases of invasive S. dimidiatum infections.

Scytalidium dimidiatum is a pigmented dematiaceous coelomycete that typically causes chronic superficial skin diseases and onychomycosis, as well as deeper infections, such as subcutaneous abscesses, mycetoma, and even fungemia in immunocompromised patients. A second species, Scytalidium hyalinum, has hyaline hyphae and arthroconidia and is considered by some authors to be an albino mutant of S...