نتایج جستجو برای: scot

تعداد نتایج: 556  

Journal: :American journal of physiology. Heart and circulatory physiology 2001
I V Turko S Marcondes F Murad

High levels of reactive species of nitrogen and oxygen in diabetes may cause modifications of proteins. Recently, an increase in protein tyrosine nitration was found in several diabetic tissues. To understand whether protein tyrosine nitration is the cause or the result of the associated diabetic complications, it is essential to identify specific proteins vulnerable to nitration with in vivo m...

1993
Hans K. Klein Daniel Lee Kleinman

Although scholarship in the social construction of technology (SCOT) has contributed much to illuminating technological development, most work using this theoretical approach is committed to an agency-centered approach. SCOT scholars have made only limited contributions to illustrating the influence of social structures. In this article, the authors argue for the importance of structural concep...

2004
Karl Schultz Brady Clark Heather Pon-Barry Elizabeth Owen Bratt Stanley Peters

We describe SCoT, a Spoken Conversational Tutor, which has been implemented in order to investigate the advantages of natural language in tutoring, especially spoken language. SCoT uses a generic architecture for conversational intelligence which has capabilities such as turn management and coordination of multi-modal input and output. SCoT also includes a set of domain independent tutorial rec...

Journal: :Genetics and molecular research : GMR 2016
B Zeng H D Yan L K Huang Y C Wang J H Wu X Huang A L Zhang C R Wang Q Mu

Roegneria kamoji Ohwi is an excellent forage grass due to its high feeding value and high resistance to some biotic and abiotic stresses. However, the start codon targeted (SCoT) polymorphism has not been conducted on R. kamoji. In this study, an orthogonal L16 (45) design was employed to investigate the effects of five factors (Mg2+, dNTPs, Taq DNA polymerase, primer, and template DNA) on the ...

2007
Hak Lae Kim Sung-Kwon Yang Seung-Jae Song John G. Breslin Hong-Gee Kim

In this paper we give an overview of the int.ere.st for a social tagging, bookmarking, and sharing service. It is based on the SCOT ontology. The SCOT ontology can represent the structure and semantics for social tagging data and provide methods for sharing and reusing them. We describe how it enables users to participate in a semantic social tagging from functional point of view and show how i...

Journal: :Anticancer research 2004
Masamitsu Sawai Masakazu Yashiro Yukio Nishiguchi Masaichi Ohira Kosei Hirakawa

BACKGROUND Monoacetoacetin (MAA) has been used experimentally as a physiological energy source in parenteral nutrition. Succinyl-CoA: 3-oxoacid CoA transferase (SCOT) is a key enzyme in the metabolism of MAA. In this study, the effect of MAA on the growth of human gastric cancer cells was examined in relation to SCOT expression. MATERIALS AND METHODS Four gastric cancer cell lines, OCUM-2M, M...

Journal: :American journal of physiology. Endocrinology and metabolism 2013
Weitao Cong Weide Ma Ting Zhao Zhongxin Zhu Yuehui Wang Yi Tan Xiaokun Li Litai Jin Lu Cai

We previously demonstrated that metallothionein (MT)-mediated protection from diabetes-induced pathological changes in cardiac tissues is related to suppression of superoxide generation and protein nitration. The present study investigated which diabetes-nitrated protein(s) mediate the development of these pathological changes by identifying the panel of nitrated proteins present in diabetic he...

Journal: :Circulation Research 2018

2004
A. J. Leigh Brown D. Lobidel C. M. Wade S. Rebus A. N. Phillips R. P. Brettle A. J. France C. S. Leen J. McMenamin A. McMillan R. D. Maw F. Mulcahy J. R. Robertson K. N. Sankar G. Scott R. Wyld J. F. Peutherer

Centre for HIV Research, Institute of Cell, Animal and Population Biology, and Department of Medical Microbiology, University of Edinburgh, Waddington Building, West Mains Road, Edinburgh, EH9 3JN Scotland: Department of Public Health Medicine, Royal Free Hospital, London NW3, England; Infectious Diseases Unit, City Hospital, Edinburgh, Scotland; King’s Cross Hospital, Dundee, Scot/and; Ruchill...

Journal: :American journal of physiology. Endocrinology and metabolism 2013
David G Cotter Rebecca C Schugar Anna E Wentz D André d'Avignon Peter A Crawford

During states of low carbohydrate intake, mammalian ketone body metabolism transfers energy substrates originally derived from fatty acyl chains within the liver to extrahepatic organs. We previously demonstrated that the mitochondrial enzyme coenzyme A (CoA) transferase [succinyl-CoA:3-oxoacid CoA transferase (SCOT), encoded by nuclear Oxct1] is required for oxidation of ketone bodies and that...

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